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Calcified Tissue International

, Volume 82, Issue 4, pp 293–299 | Cite as

Relationship of Total Body Fat Mass to Bone Area in New Zealand Five-Year-Olds

  • Ailsa GouldingEmail author
  • Rachael W. Taylor
  • Andrea M. Grant
  • Linda Murdoch
  • Sheila M. Williams
  • Barry J. Taylor
Article

Abstract

Fat mass was recently shown to be a positive determinant of bone mass and size independently of lean mass in a birth cohort of British 9-year-olds. The present study was undertaken to investigate whether similar relationships are evident in younger, preschool children. Height and weight were measured, and a total-body dual-energy X-ray absorptiometric scan was performed on 194 preschool New Zealand children (81 girls, 113 boys) participating in the Dunedin birth cohort Family, Lifestyle, Activity, Movement, and Eating (FLAME) study close to their fifth birthday. Relationships of total-body fat mass and lean mass to total-body-less-head (TBLH) bone area and TBLH bone mineral content (BMC) were evaluated using linear regression. Girls had higher mean fat mass (3.9 vs. 3.2 kg) and lower lean mass (14.5 vs. 15.2 kg) than boys (P < 0.001), but their heights, weights, and TBLH bone area were similar. Although a given weight of lean tissue was associated with greater increases in TBLH area than a given weight of fat tissue, our results show that fat mass was an independent predictor of TBLH bone area (R = 0.79, P < 0.001) and TBLH BMC (R 2 = 0.74, P < 0.001) in data adjusted for socioeconomic status, ethnic group, lean mass, and height. We conclude that increased fat mass is associated with outward expansion of the TBLH skeletal envelope (wider bones) independently of height and lean mass in very young children.

Keywords

Birth cohort Dual-energy X-ray absorptiometry Bone size Fat mass Lean mass 

Notes

Acknowledgements

We are very grateful to all the children and families participating in the FLAME study and thank Aveen Hewitt, Shirley Jones, and Tina Forrester for excellent technical assistance. The study was funded by grants from the Child Health Research Foundation of New Zealand, the National Heart Foundation of New Zealand, and the Caversham Foundation.

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Copyright information

© Springer Science+Business Media, LLC 2008

Authors and Affiliations

  • Ailsa Goulding
    • 1
    Email author
  • Rachael W. Taylor
    • 1
  • Andrea M. Grant
    • 1
  • Linda Murdoch
    • 2
  • Sheila M. Williams
    • 3
  • Barry J. Taylor
    • 2
  1. 1.Department of Medical and Surgical SciencesUniversity of OtagoDunedinNew Zealand
  2. 2.Department of Women’s and Children’s HealthUniversity of OtagoDunedinNew Zealand
  3. 3.Department of Preventive and Social MedicineUniversity of OtagoDunedinNew Zealand

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