Calcified Tissue International

, Volume 73, Issue 2, pp 108–114 | Cite as

A 3-Year Longitudinal Study of the Effect of Physical Activity on the Accrual of Bone Mineral Density in Healthy Adolescent Males

Clinical Investigations

Abstract

It has previously been suggested that physical activity predominantly influences the accumulation of bone density before puberty. The purpose of the present study was to examine the effect of physical activity on the accumulation of bone mass in male athletes between 16 and 19 years of age. The cohort studied consisted of 12 badminton players (aged 16.1 ± 0.5), 20 ice hockey players (aged 16.1 ± 0.5), and 24 age-matched controls (aged 16.1 ± 0.6). The bone mineral density (BMD, g/cm2) of the total body, spine, dominant and nondominant humerus, head and femoral neck was measured twice with a 3-year interval by dual energy X-ray absorptiometry (DXA). In addition, at the femoral neck, volumetric bone mineral density (vBMD, mg/cm3) was estimated. At baseline, the athletes as a whole group had significantly higher BMD at the total body (P = 0.03), dominant (P = 0.006) and nondominant humerus (P = 0.009) and femoral neck (P = 0.007) compared to the controls. At the 3-year followup, the athletes had significantly higher BMD at all sites (total body; P = 0.003, spine; P = 0.02, dominant humerus; P = 0.001, nondominant humerus; P = <0.001, femoral neck; P = 0.001) except for the head (P = 0.91) compared with controls. The athletes also had higher vBMD at the femoral neck compared with the controls (P = 0.01). Furthermore, to be an athlete was found to be independently associated with a higher increase in nondominant humerus BMD (β = 0.24; P < 0.05) and femoral neck BMD (β = 0.30; P < 0.05) compared with the controls, during the study period. In summary, these results suggests that it is possible to achieve continuous gains in bone mass in sites exposed to osteogenic stimulation after puberty in males by engaging in weight-bearing physical activity.

Keywords

Bone mineral density Peak bone mass Boys, physical activity 

Notes

Acknowledgements

This study was supported by grants from Länsförsäkringar insurance company, project number P4/01, and from the Swedish National Center for Research in Sports, project number 112/01.

References

  1. 1.
    .1993Consensus development conference: diagnosis, prophylaxis, and treatment of osteoporosisAm J Med94646650PubMedGoogle Scholar
  2. 2.
    Browner, WS, Pressman, AR, Nevitt, MC, Cummings, SR 1996Mortality following fractures in older women. The study of osteoporotic fractures.Arch Intern Med15615211551PubMedGoogle Scholar
  3. 3.
    Cooper, C, Atkinson, EJ, Jacobsen, SJ, O’Fallon, WM, Melton, LJD 1993Population-based study of survival after osteoporotic fractures.Am J Epidemiol13710011005PubMedGoogle Scholar
  4. 4.
    Nevitt, MC, Ettinger, B, Black, DM,  et al. 1998The association of radiographically detected vertebral fractures with back pain and function: a prospective study.Ann Intern Med128793800PubMedGoogle Scholar
  5. 5.
    Eisman, JA 1999Genetics of osteoporosis.Endocr Rev20788804PubMedGoogle Scholar
  6. 6.
    Jouanny, P, Guillemin, F, Kuntz, C, Jeandel, C, Pourel, J 1995Environmental and genetic factors affecting bone mass. Similarity of bone density among members of healthy families.Arthritis Rheum386167PubMedGoogle Scholar
  7. 7.
    Seeman, E, Hopper, JL, Bach, LA,  et al. 1989Reduced bone mass in daughters of women with osteoporosis.N Engl J Med320554558PubMedGoogle Scholar
  8. 8.
    Slemenda, CW, Christian, JC, Williams, CJ, Norton, JA, Johnston Jr, CC 1991Genetic determinants of bone mass in adult women: a reevaluation of the twin model and the potential importance of gene interaction on heritability estimates.J Bone Miner Res6561567PubMedGoogle Scholar
  9. 9.
    Cummings, SR, Nevitt, MC, Browner, WS,  et al. 1995Risk factors for hip fracture in white women. Study of Osteoporotic Fractures Research Group.N Engl J Med332767773PubMedGoogle Scholar
  10. 10.
    Lu, PW, Briody, JN, Ogle, GD,  et al. 1994Bone mineral density of total body, spine, and femoral neck in children and young adults: a cross-sectional and longitudinal study.J Bone Miner Res914511458PubMedGoogle Scholar
  11. 11.
    Teegarden, D, Proulx, WR, Martin, BR,  et al. 1995Peak bone mass in young women.J Bone Miner Res10711715PubMedGoogle Scholar
  12. 12.
    Hui, SL, Slemenda, CW, Johnston Jr, CC 1990The contribution of bone loss to postmenopausal osteoporosis.Osteoporos Int13034PubMedGoogle Scholar
  13. 13.
    Johnston Jr, CC, Slemenda, CW 1994Peak bone mass, bone loss and risk of fracture.Osteoporos Int44345PubMedGoogle Scholar
  14. 14.
    Bradney, M, Pearce, G, Naughton, G,  et al. 1998Moderate exercise during growth in prepubertal boys: changes in bone mass, size, volumetric density, and bone strength. A controlled prospective study.J Bone Miner Res1318141821PubMedGoogle Scholar
  15. 15.
    French, SA, Fulkerson, JA, Story, M 2000Increasing weight-bearing physical activity and calcium intake for bone mass growth in children and adolescents: a review of intervention trials.Prev Med31722731CrossRefPubMedGoogle Scholar
  16. 16.
    Trudeau, F, Laurencelle, L, Tremblay, J, Rajic, M, Shephard, RJ 1999Daily primary school physical education: effects on physical activity during adult life.Med Sci Sports Exerc31111117PubMedGoogle Scholar
  17. 17.
    O’Connor, JA, Lanyon, LE, MacFie, H 1982The influence of strain rate on adaptive bone remodelling.J Biomech15767781PubMedGoogle Scholar
  18. 18.
    Raab-Cullen, DM, Akhter, MP, Kimmel, DB, Recker, RR 1994Bone response to alternate-day mechanical loading of the rat tibia.J Bone Miner Res9203211PubMedGoogle Scholar
  19. 19.
    Rubin, CT, Lanyon, LE 1984Regulation of bone formation by applied dynamic loads.J Bone Joint Surg Am66397402PubMedGoogle Scholar
  20. 20.
    Rubin, CT, Lanyon, LE 1985Regulation of bone mass by mechanical strain magnitude.Calcif Tissue Int37411417PubMedGoogle Scholar
  21. 21.
    Lanyon, LE 1992Control of bone architecture by functional load bearing.J Bone Miner Res7S369S375PubMedGoogle Scholar
  22. 22.
    Lanyon, LE, Rubin, CT, Baust, G 1986Modulation of bone loss during calcium insufficiency by controlled dynamic loading.Calcif Tissue Int38209216PubMedGoogle Scholar
  23. 23.
    Fuchs, RK, Bauer, JJ, Snow, CM 2001Jumping improves hip and lumbar spine bone mass in prepubescent children: a randomized controlled trial.J Bone Miner Res16148156PubMedGoogle Scholar
  24. 24.
    Heinonen, A, Sievanen, H, Kannus, P, Oja, P, Pasanen, M, Vuori, I 2000High-impact exercise and bones of growing girls: a 9-month controlled trial.Osteoporos Int1110101017CrossRefPubMedGoogle Scholar
  25. 25.
    Mackelvie, KJ, McKay, HA, Khan, KM, Crocker, PR 2001A school-based exercise intervention augments bone mineral accrual in early pubertal girls.J Pediatr139501507CrossRefPubMedGoogle Scholar
  26. 26.
    Tanner, JM 1962Growth at adolescence.Blackwell Scientific PublicationsPhiladelphia, PAGoogle Scholar
  27. 27.
    Nordstrom, P, Pettersson, U, Lorentzon, R 1998Type of physical activity, muscle strength, and pubertal stage as determinants of bone mineral density and bone area in adolescent boys.J Bone Miner Res1311411148PubMedGoogle Scholar
  28. 28.
    Orwoll, ES, Oviatt, SK, Biddle, JA 1993Precision of dual-energy x-ray absorptiometry: development of quality controls and their application in longitudinal studies.J Bone Miner Res8693699PubMedGoogle Scholar
  29. 29.
    Sievänen, H, Oja, P, Vouri, I 1992Precision of dual-energy x-ray absorptiometry in determining bone mineral content of various skeletal sites.J Nucl Med3311371142PubMedGoogle Scholar
  30. 30.
    Nordstrom, P, Lorentzon, R 1996Site-specific bone mass differences of the lower extremities in 17-year-old ice hockey players.Calcif Tissue Int59443448CrossRefPubMedGoogle Scholar
  31. 31.
    Sundberg, M, Gardsell, P, Johnell, O,  et al. 2001Peripubertal moderate exercise increases bone mass in boys but not in girls: a population-based intervention study.Osteoporos Int12230238CrossRefPubMedGoogle Scholar
  32. 32.
    Greendale, GA, Barrett-Connor, E, Edelstein, S, Ingles, S, Haile, R 1995Lifetime leisure exercise and osteoporosis. The Rancho Bernardo Study.Am J Epidemiol141951959PubMedGoogle Scholar
  33. 33.
    Brahm, H, Mallmin, H, Michaelsson, K, Strom, H, Ljunghall, S 1998Relationships between bone mass measurements and lifetime physical activity in a Swedish population.Calcif Tissue Int62400412CrossRefPubMedGoogle Scholar
  34. 34.
    Bailey, DA, McKay, HA, Mirwald, RL, Crocker, PR, Faulkner, RA 1999A six-year longitudinal study of the relationship of physical activity to bone mineral accrual in growing children: the University of Saskatchewan bone mineral accrual study.J Bone Miner Res1416721679PubMedGoogle Scholar
  35. 35.
    Bennell, KL, Malcolm, SA, Khan, KM,  et al. 1997Bone mass and bone turnover in power athletes, endurance athletes, and controls: a 12-month longitudinal study.Bone20477484CrossRefPubMedGoogle Scholar
  36. 36.
    Welten, DC, Kemper, HC, Post, GB,  et al. 1994Weight-bearing activity during youth is a more important factor for peak bone mass than calcium intake.J Bone Miner Res910891096PubMedGoogle Scholar
  37. 37.
    Blumenthal, JA, Emery, CF, Madden, DJ,  et al. 1991Effects of exercise training on bone density in older men and women.J Am Geriatr Soc3910651070PubMedGoogle Scholar
  38. 38.
    Kannus, P, Haapasalo, H, Sankelo, M,  et al. 1995Effect of starting age of physical activity on bone mass in the dominant arm of tennis and squash players.Ann Intern Med1232731PubMedGoogle Scholar
  39. 39.
    Lorentzon, R, Wedren, H, Pietila, T 1988Incidence, nature, and causes of ice hockey injuries. A three-year prospective study of a Swedish elite ice hockey team.Am J Sports Med16392396PubMedGoogle Scholar
  40. 40.
    Nordstrom, P, Nordstrom, G, Thorsen, K, Lorentzon, R 1996Local bone mineral density, muscle strength, and exercise in adolescent boys: a comparative study of two groups with different muscle strength and exercise levels.Calcif Tissue Int58402408CrossRefPubMedGoogle Scholar
  41. 41.
    Nordstrom, P, Thorsen, K, Bergstrom, E, Lorentzon, R 1996High bone mass and altered relationships between bone mass, muscle strength, and body constitution in adolescent boys on a high level of physical activity.Bone19189195CrossRefPubMedGoogle Scholar
  42. 42.
    Calbet, JA, Moysi, JS, Dorado, C, Rodriguez, LP 1998Bone mineral content and density in professional tennis players.Calcif Tissue Int62491496CrossRefPubMedGoogle Scholar
  43. 43.
    Haapasalo, H, Kannus, P, Sievanen, H,  et al. 1998Effect of long-term unilateral activity on bone mineral density of female junior tennis players.J Bone Miner Res13310319PubMedGoogle Scholar
  44. 44.
    Fehling, PC, Alekel, L, Clasey, J, Rector, A, Stillman, RJ 1995A comparison of bone mineral densities among female athletes in impact loading and active loading sports.Bone17205210CrossRefPubMedGoogle Scholar
  45. 45.
    Heinonen, A, Oja, P, Kannus, P, Sievanen, H, Manttari, A, Vuori, I 1993Bone mineral density of female athletes in different sports.Bone Miner23114PubMedGoogle Scholar
  46. 46.
    Lee, EJ, Long, KA, Risser, WL, Poindexter, HB, Gibbons, WE, Goldzieher, J 1995Variations in bone status of contralateral and regional sites in young athletic women.Med Sci Sports Exerc2713541361PubMedGoogle Scholar

Copyright information

© Springer-Verlag 2003

Authors and Affiliations

  1. 1.Medicine, Department of Public Health and Clinical MedicineUmeå University, 901 87 UmeåSweden
  2. 2.Sports Medicine, Department of Surgical and Perioperative SciencesUmeå University, 901 87 UmeåSweden
  3. 3.Department of Musculoskeletal Research, National Institute for Working LifeUmeå University, 901 87 UmeåSweden
  4. 4.Department of Geriatric MedicineUmeå University, 901 87 UmeåSweden

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