Advertisement

Experimental Brain Research

, Volume 117, Issue 1, pp 161–164 | Cite as

Input-increase and input-decrease types of cortical reorganization after upper extremity amputation in humans

  • T. Elbert
  • Annette Sterr
  • Herta Flor
  • Brigitte Rockstroh
  • Stefan Knecht
  • Christo Pantev
  • Christian Wienbruch
  • Edward Taub
RESEARCH NOTE

Abstract 

A plastic remodeling of regions in somatosensory cortex has previously been observed to occur in separate experimental paradigms in response to loss of somatosensory input and to increase in input. In this study, both types of cortical reorganization have been observed to occur concurrently in the same adult human nervous system as a result of a single intervention. Following upper extremity amputation, magnetic source imaging revealed that tactile stimulation of the lip evoked responses not only in the area of the somatosensory cortex corresponding to the face, but also within the cortical region that would normally correspond to the now absent hand. This “invasion” of the cortical amputation zone was accompanied by a significant increase in the size of the representation of the digits of the intact hand, presumably as a result of an increased importance of sensory stimulation consequent to increased dependence on that hand imposed by the loss of the contralateral extremity.

Key words Somatosensory Cortex Plasticity Amputation Magnetoencephalography 

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

Copyright information

© Springer-Verlag Berlin Heidelberg 1997

Authors and Affiliations

  • T. Elbert
    • 1
  • Annette Sterr
    • 1
  • Herta Flor
    • 2
  • Brigitte Rockstroh
    • 1
  • Stefan Knecht
    • 3
  • Christo Pantev
    • 3
  • Christian Wienbruch
    • 1
  • Edward Taub
    • 4
  1. 1.University of Konstanz, Postfach 5560-d23, D-78464 Konstanz, Germany Fax: +49–7531–88–2891, e-mail: thomas.elbert@uni-konstanz.deDE
  2. 2.Humboldt-University, Hausvogteiplatz 5–7, D-10117 Berlin, GermanyDE
  3. 3.University of Münster, Kardinal-von Galen-Ring 10, D-48129 Münster, GermanyDE
  4. 4.University of Alabama at Birmingham, 415 Campbell Hall, Birmingham, AL 35294–1170, USAUS

Personalised recommendations