Experimental Brain Research

, Volume 234, Issue 4, pp 1033–1045 | Cite as

Corticomotor control of lumbar multifidus muscles is impaired in chronic low back pain: concurrent evidence from ultrasound imaging and double-pulse transcranial magnetic stimulation

  • Hugo Massé-Alarie
  • Louis-David Beaulieu
  • Richard Preuss
  • Cyril Schneider
Research Article

Abstract

Chronic low back pain (CLBP) is often associated with impaired control of deep trunk muscles and reorganization of the primary motor areas (M1). Precisely, functional changes of the lumbar multifidus muscles (MF) involved in spine stability may be of special interest in rehabilitation. Therefore, we tested MF corticomotor control using double transcranial magnetic stimulation (TMS) paradigms for the first time in this muscle and examined its link with MF volitional activation. Eleven individuals with lateralized CLBP and 13 pain-free participants were recruited. Ultrasound imaging enabled measurement of MF volitional isometric contraction in prone lying. TMS of MF M1 area was used to test hemispheric excitability and mechanisms in relation to motor programming, i.e., active motor threshold (AMT), amplitude of motor-evoked potentials and short-interval intracortical inhibition (SICI) and facilitation (SICF). In CLBP, SICI level was lower in the left hemisphere and MF volitional contraction was not related to AMT (M1 excitability), conversely to what was observed in the pain-free group. No other between-group difference was detected. These original findings support a plasticity of cortical maps controlling paravertebral muscles and likely including a different motor strategy for the control of MF. Changes of M1 function may thus underlie impaired motor control of lumbopelvic spine and pain persistence in CLBP.

Keywords

Primary motor cortex Intracortical inhibition and facilitation Transcranial magnetic stimulation Ultrasound imaging Multifidus motor control Chronic low back pain 

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Copyright information

© Springer-Verlag Berlin Heidelberg 2015

Authors and Affiliations

  • Hugo Massé-Alarie
    • 1
    • 2
  • Louis-David Beaulieu
    • 1
  • Richard Preuss
    • 2
    • 3
  • Cyril Schneider
    • 1
    • 4
  1. 1.Laboratory of Clinical Neuroscience and NeurostimulationNeuroscience Division of the Centre de Recherche du CHU de QuébecQuebec CityCanada
  2. 2.Constance Lethbridge Rehabilitation Center Research Site of the CRIRMontrealCanada
  3. 3.School of Physical and Occupational TherapyMcGill UniversityMontrealCanada
  4. 4.Department of Rehabilitation, Faculty of MedicineUniversité LavalQuébec CityCanada

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