Experimental Brain Research

, Volume 211, Issue 2, pp 243–250 | Cite as

Modulation of the motor system during visual and auditory language processing

  • Ludovica LabrunaEmail author
  • Miguel Fernández-del-Olmo
  • Ayelet Landau
  • Julie Duqué
  • Richard B. Ivry
Research Article


Studies of embodied cognition have demonstrated the engagement of the motor system when people process action-related words and concepts. However, research using transcranial magnetic stimulation (TMS) to examine linguistic modulation in primary motor cortex has produced inconsistent results. Some studies report that action words produce an increase in corticospinal excitability; others, a decrease. Given the differences in methodology and modality, we re-examined this issue, comparing conditions in which participants either read or listened to the same set of action words. In separate blocks of trials, participants were presented with lists of words in the visual and auditory modality, and a TMS pulse was applied over left motor cortex, either 150 or 300 ms after the word onset. Motor evoked potentials (MEPs) elicited were larger following the presentation of action words compared with control words. However, this effect was only observed when the words were presented visually; no changes in MEPs were found when the words were presented auditorily. A review of the TMS literature on action word processing reveals a similar modality effect on corticospinal excitability. We discuss different hypotheses that might account for this differential modulation of action semantics by vision and audition.


TMS Language Embodiment Action Reading Listening Visual Auditory 



This work was supported by a grant from the US-Israel Binational Science Foundation (BSF007350) and a grant from Xunta de Galicia, Spain (PGIDIT06PXIB160333PR).


  1. Aziz-Zadeh L, Maeda F, Zaidel E, Mazziotta J, Iacoboni M (2002) Lateralization in motor facilitation during action observation: a TMS study. Exp Brain Res 144(1):127–131PubMedCrossRefGoogle Scholar
  2. Aziz-Zadeh L, Wilson SM, Rizzolatti G, Iacoboni M (2006) Congruent embodied representations for visually presented actions and linguistic phrases describing actions. Curr Biol 16(18):1818–1823PubMedCrossRefGoogle Scholar
  3. Boulenger V, Hauk O, Pulvermuller F (2009) Grasping ideas with the motor system: semantic somatotopy in idiom comprehension. Cereb Cortex 19(8):1905–1914PubMedCrossRefGoogle Scholar
  4. Buccino G, Binkofski F, Riggio L (2004) The mirror neuron system and action recognition. Brain Lang 89(2):370–376PubMedCrossRefGoogle Scholar
  5. Buccino G, Riggio L, Melli G, Binkofski F, Gallese V, Rizzolatti G (2005) Listening to action-related sentences modulates the activity of the motor system: a combined TMS and behavioral study. Brain Res 24(3):355–363Google Scholar
  6. Fadiga L, Fogassi L, Pavesi G, Rizzolatti G (1995) Motor facilitation during action observation: a magnetic stimulation study. J Neurophysiol 73(6):2608–2611PubMedGoogle Scholar
  7. Fadiga L, Craighero L, Olivier E (2005) Human motor cortex excitability during the perception of others’ action. Curr Opin Neurobiol 15(2):213–218PubMedCrossRefGoogle Scholar
  8. Feldman J (2006) From molecule to metaphor. A neural theory of language. The MITT Press, CambridgeGoogle Scholar
  9. Feldman J, Narayanan S (2004) Embodied meaning in a neural theory of language. Brain Lang 89(2):385–392PubMedCrossRefGoogle Scholar
  10. Fourkas AD, Avenanti A, Urgesi C, Aglioti SM (2006) Corticospinal facilitation during first and third person imagery. Exp Brain Res 168(1–2):143–151Google Scholar
  11. Gangitano M, Mottaghy FM, Pascual-Leone A (2001) Phase-specific modulation of cortical motor output during movement observation. Neuroreport 12(7):1489–1492PubMedCrossRefGoogle Scholar
  12. Gazzola V, Keysers C (2009) The observation and execution of actions share motor and somatosensory voxels in all tested subjects: single-subject analyses of unsmoothed fMRI data. Cereb Cortex 19(6):1239–1255PubMedCrossRefGoogle Scholar
  13. Gazzola V, Aziz-Zadeh L, Keysers C (2006) Empathy and the somatotopic auditory mirror system in humans. Curr Biol 16(18):1824–1829PubMedCrossRefGoogle Scholar
  14. Glenberg AM, Kaschak MP (2002) Grounding language in action. Psychon Bull Rev 9(3):558–565PubMedCrossRefGoogle Scholar
  15. Glenberg AM, Sato M, Cattaneo L, Riggio L, Palumbo D, Buccino G (2008) Processing abstract language modulates motor system activity. Q J Exp Psychol 61(6):905–919CrossRefGoogle Scholar
  16. Hauk O, Johnsrude I, Pulvermuller F (2004) Somatotopic representation of action words in human motor and premotor cortex. Neuron 41(2):301–307PubMedCrossRefGoogle Scholar
  17. Hauk O, Shtyrov Y, Pulvermuller F (2008) The time course of action and action-word comprehension in the human brain as revealed by neurophysiology. J Physiol, Paris 102(1–3):50–58CrossRefGoogle Scholar
  18. Kohler E, Keysers C, Umilta MA, Fogassi L, Gallese V, Rizzolatti G (2002) Hearing sounds, understanding actions: action representation in mirror neurons. Science (New York, NY) 297(5582):846–848CrossRefGoogle Scholar
  19. Labruna L, Fernández-del-Olmo M, Ivry RB Comparison of different baseline conditions in evaluating factors that influence motor cortex excitability. Brain Stimul (in press)Google Scholar
  20. Lahav A, Saltzman E, Schlaug G (2007) Action representation of sound: audiomotor recognition network while listening to newly acquired actions. J Neurosci 27(2):308–314PubMedCrossRefGoogle Scholar
  21. Liberman AM, Mattingly IG (1989) A specialization for speech perception. Science (New York, NY) 243(4890):489–494CrossRefGoogle Scholar
  22. Mahon BZ, Caramazza A (2008) A critical look at the embodied cognition hypothesis and a new proposal for grounding conceptual content. J Physiol, Paris 102(1–3):59–70CrossRefGoogle Scholar
  23. Morin O, Grezes J (2008) What is “mirror” in the premotor cortex? A review. Neurophysiol Clin 38(3):189–195PubMedCrossRefGoogle Scholar
  24. Oldfield RC (1971) The assessment and analysis of handedness: the Edinburgh inventory. Neuropsychologia 9(1):97–113PubMedCrossRefGoogle Scholar
  25. Oliveri M, Finocchiaro C, Shapiro K, Gangitano M, Caramazza A, Pascual-Leone A (2004) All talk and no action: a transcranial magnetic stimulation study of motor cortex activation during action word production. J Cogn Neurosci 16(3):374–381Google Scholar
  26. Papeo L, Vallesi A, Isaja A, Rumiati RI (2009) Effects of TMS on different stages of motor and non-motor verb processing in the primary motor cortex. PloS One 4(2):e4508PubMedCrossRefGoogle Scholar
  27. Patuzzo S, Fiaschi A, Manganotti P (2003) Modulation of motor cortex excitability in the left hemisphere during action observation: a single- and paired-pulse transcranial magnetic stimulation study of self- and non-self-action observation. Neuropsychologia 41(9):1272–1278Google Scholar
  28. Pizzamiglio L, Aprile T, Spitoni G, Pitzalis S, Bates E, D’Amico S et al (2005) Separate neural systems for processing action- or non-action-related sounds. NeuroImage 24(3):852–861PubMedCrossRefGoogle Scholar
  29. Pulvermuller F, Fadiga L (2010) Active perception: sensorimotor circuits as a cortical basis for language. Nat rev 11(5):351–360CrossRefGoogle Scholar
  30. Pulvermuller F, Hauk O, Nikulin VV, Ilmoniemi RJ (2005) Functional links between motor and language systems. Eur J Neurosci 21(3):793–797PubMedCrossRefGoogle Scholar
  31. Recanzone GH (2009) Interactions of auditory and visual stimuli in space and time. Hear Res 258(1–2):89–99PubMedCrossRefGoogle Scholar
  32. Rizzolatti G, Craighero L (2004) The mirror-neuron system. Annu Rev Neurosci 27:169–192PubMedCrossRefGoogle Scholar
  33. Shtyrov Y, Kujala T, Pulvermuller F (2010) Interactions between language and attention systems: early automatic lexical processing? J Cogn Neurosci 22(7):1465–1478PubMedCrossRefGoogle Scholar
  34. Strafella AP, Paus T (2000) Modulation of cortical excitability during action observation: a transcranial magnetic stimulation study. Neuroreport 11(10):2289–2292PubMedCrossRefGoogle Scholar
  35. Tettamanti M, Buccino G, Saccuman MC, Gallese V, Danna M, Scifo P et al (2005) Listening to action-related sentences activates fronto-parietal motor circuits. J Cogn Neurosci 17(2):273–281PubMedCrossRefGoogle Scholar
  36. Tomasino B, Fink GR, Sparing R, Dafotakis M, Weiss PH (2008) Action verbs and the primary motor cortex: a comparative TMS study of silent reading, frequency judgments, and motor imagery. Neuropsychologia 46(7):1915–1926PubMedCrossRefGoogle Scholar

Copyright information

© Springer-Verlag 2011

Authors and Affiliations

  • Ludovica Labruna
    • 1
    • 2
    Email author
  • Miguel Fernández-del-Olmo
    • 3
  • Ayelet Landau
    • 2
  • Julie Duqué
    • 4
  • Richard B. Ivry
    • 2
  1. 1.Health Science DepartmentUniversity of MoliseMoliseItaly
  2. 2.Department of PsychologyUniversity of CaliforniaBerkeleyUSA
  3. 3.Departamento de Educación Física e Deportiva, Facultade de Ciencias do Deporte e a Educación FísicaINEFGaliciaSpain
  4. 4.Institute of NeuroscienceUniversité catholique de LouvainLouvain-la-NeuveBelgium

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