Experimental Brain Research

, 198:113 | Cite as

Challenges in quantifying multisensory integration: alternative criteria, models, and inverse effectiveness

  • Barry E. Stein
  • Terrence R. Stanford
  • Ramnarayan Ramachandran
  • Thomas J. PerraultJr.
  • Benjamin A. Rowland
Research Article

Abstract

Single-neuron studies provide a foundation for understanding many facets of multisensory integration. These studies have used a variety of criteria for identifying and quantifying multisensory integration. While a number of techniques have been used, an explicit discussion of the assumptions, criteria, and analytical methods traditionally used to define the principles of multisensory integration is lacking. This was not problematic when the field was small, but with rapid growth a number of alternative techniques and models have been introduced, each with its own criteria and sets of implicit assumptions to define and characterize what is thought to be the same phenomenon. The potential for misconception prompted this reexamination of traditional approaches in order to clarify their underlying assumptions and analytic techniques. The objective here is to review and discuss traditional quantitative methods advanced in the study of single-neuron physiology in order to appreciate the process of multisensory integration and its impact.

Keywords

Sensory Cross-modal Computation Vision Auditory Somatosensory 

Notes

Acknowledgments

We thank Nancy London for technical assistance. Part of the research discussed here was supported by NIH grants EY016716 and NS36916.

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Copyright information

© Springer-Verlag 2009

Authors and Affiliations

  • Barry E. Stein
    • 1
  • Terrence R. Stanford
    • 1
  • Ramnarayan Ramachandran
    • 1
  • Thomas J. PerraultJr.
    • 1
  • Benjamin A. Rowland
    • 1
  1. 1.Department of Neurobiology and AnatomyWake Forest University School of MedicineWinston-SalemUSA

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