Experimental Brain Research

, Volume 192, Issue 4, pp 627–633

Symptoms of hyperactivity and inattention can mediate deficits of postural stability in developmental dyslexia

  • Kim S. H. Rochelle
  • Caroline Witton
  • Joel B. Talcott
Research Article

Abstract

Developmental dyslexia is a reading disorder associated with impaired postural control. However, such deficits are also found in attention deficit hyperactivity disorder (ADHD), which is present in a substantial subset of dyslexia diagnoses. Very few studies of balance in dyslexia have assessed ADHD symptoms, thereby motivating the hypothesis that such measures can account for the group differences observed. In this study, we assessed adults with dyslexia and similarly aged controls on a battery of cognitive, literacy and attention measures, alongside tasks of postural stability. Displacements of centre of mass to perturbations of posture were measured in four experimental conditions using digital optical motion capture. The largest group differences were obtained in conditions where cues to the support surface were reduced. Between-group differences in postural sway and in sway variability were largely accounted for by co-varying hyperactivity and inattention ratings, however. These results therefore suggest that postural instability in dyslexia is more strongly associated with symptoms of ADHD than to those specific to reading impairment.

Keywords

Developmental dyslexia Posture Balance Attention deficit hyperactivity disorder Developmental co-ordination disorder Comorbidity 

Abbreviations

ADHD

Attention deficit hyperactivity disorder

DCD

Developmental co-ordination disorder

FSIQ

Full scale intelligence quotient

References

  1. American Psychiatric Association (2000) Diagnostic and statistical manual of mental disorders, text revision (DSM-IV-TR). Author, WashingtonGoogle Scholar
  2. Anderson CM, Lowen SB, Renshaw PF (2006) Emotional task dependent low-frequency fluctuations and methylphenidate: wavelet scaling analysis of 1/f-type fluctuations in fMRI of the cerebellar vermis. J Neurosci Methods 151:52–61PubMedCrossRefGoogle Scholar
  3. Balasubramaniam R, Wing AM (2002) The dynamics of standing balance. Trends Cogn Sci 6:531–536PubMedCrossRefGoogle Scholar
  4. Barkley RA, Murphy KR (1998) Attention-deficit hyperactivity disorder: a clinical workbook. The Guilford Press, New YorkGoogle Scholar
  5. Berquin PC, Giedd JN, Jacobsen LK, Burger SD, Krain AL, Rapoport JL et al (1998) Cerebellum in attention-deficit hyperactivity disorder: a morphometric MRI study. Neurology 50:1087–1093PubMedGoogle Scholar
  6. Bishop DVM (2002) Cerebellar abnormalities in developmental dyslexia: cause, correlate or consequence? Cortex 38:491–498PubMedCrossRefGoogle Scholar
  7. Bussing R, Grudnik J, Mason D, Wasiak M, Leonard C (2002) ADHD and conduct disorder: an MRI study in a community sample. World J Biol Psychiatry 3:216–220PubMedCrossRefGoogle Scholar
  8. Castellanos FX, Giedd JN, Berquin PC, Walter JM, Sharp W, Tran T et al (2001) Quantitative brain magnetic resonance imaging in girls with attention-deficit/hyperactivity disorder. Arch Gen Psychiatry 58:289–295PubMedCrossRefGoogle Scholar
  9. Castellanos FX, Sonuga-Barke EJS, Scheres A, Di Martino A, Hyde C, Walters JR (2005) Varieties of attention-deficit/hyperactivity disorder-related intra-individual variability. Biol Psychiatry 57:1416–1423PubMedCrossRefGoogle Scholar
  10. Castellanos FX, Tannock R (2002) Neuroscience of attention-deficit hyperactivity disorder: the search for endophenotypes. Nat Rev Neurosci 3:617–628PubMedGoogle Scholar
  11. Cohen J (1988) Statistical power analysis for the behavioral sciences, 2nd edn. Academic Press, New YorkGoogle Scholar
  12. Diamond A (2000) Close interrelation of motor development and cognitive development and of the cerebellum and prefrontal cortex. Child Dev 71:44–56PubMedCrossRefGoogle Scholar
  13. Fawcett AJ, Nicolson RI (1998) The dyslexia adult screening test (DAST). The Psychological Corporation, LondonGoogle Scholar
  14. Fawcett AJ, Nicolson RI (1999) Performance of dyslexic children on cerebellar and cognitive tests. J Mot Behav 31:68–78PubMedCrossRefGoogle Scholar
  15. Fawcett AJ, Nicolson RI (2004) The dyslexia screening test-junior (DST-J). Harcourt Assessment, LondonGoogle Scholar
  16. Fawcett AJ, Nicolson RI, Dean P (1996) Impaired performance of children with dyslexia on a range of cerebellar tasks. Ann Dyslexia 46:259–283CrossRefGoogle Scholar
  17. Ghez C, Thach WT (2000) The cerebellum. In: Kandel ER, Schwartz JH, Jessell TR (eds) Principles of neural science (4th edn) International edition. McGraw-Hill, London, pp 832–852Google Scholar
  18. Gilger JW, Kaplan BJ (2001) Atypical brain development: a conceptual framework for understanding developmental learning disabilities. Dev Neuropsychol 20:465–481PubMedCrossRefGoogle Scholar
  19. Habib M (2000) The neurological basis of developmental dyslexia: an overview and working hypothesis. Brain 123:2373–2399PubMedCrossRefGoogle Scholar
  20. Hill DE, Yeo RA, Campbell RA, Hart B, Vigil J, Brooks W (2003) Magnetic resonance imaging correlates of attention-deficit/hyperactivity disorder in children. Neuropsychology 17:496–506PubMedCrossRefGoogle Scholar
  21. Horak FB, Nashner LM, Diener HC (1990) Postural strategies associated with somatosensory and vestibular loss. Exp Brain Res 82:167–177PubMedCrossRefGoogle Scholar
  22. James CR (2004) Considerations of movement variability in biomechanics research. In: Stergiou N (ed) Innovative analyses of human movement: analytical tools for human movement research. Human Kinetics, Leeds, pp 29–62Google Scholar
  23. Kadesjö B, Gillberg C (2001) The comorbidity of ADHD in the general population of Swedish school-age children. J Child Psychol Psychiatry 42:487–492PubMedCrossRefGoogle Scholar
  24. Kaplan BJ, Wilson BN, Dewey D, Crawford SG (1998) DCD may not be a discrete disorder. Hum Mov Sci 17:471–490CrossRefGoogle Scholar
  25. Karmiloff-Smith AS (1998) Development itself is the key to understanding developmental disorders. Trends Cogn Sci 2:389–398CrossRefGoogle Scholar
  26. Krain AL, Castellanos FX (2006) Brain development and ADHD. Clin Psychol Rev 26:433–444PubMedCrossRefGoogle Scholar
  27. Maki BE, McIlroy WE (1996) Influence of arousal and attention on the control of postural sway. J Vestib Res 6:53–59PubMedCrossRefGoogle Scholar
  28. Melvill Jones G (2000) Posture. In: Kandel ER, Schwartz JH, Jessell TR (eds) Principles of neural science (4th edn) International edition. McGraw-Hill, London, pp 816–831Google Scholar
  29. Middleton FA, Strick PL (1998) Cerebellar output: motor and cognitive channels. Trends Cogn Sci 2:348–354CrossRefGoogle Scholar
  30. Moe-Nilssen R, Helbostad JL, Talcott JB, Toennessen FE (2003) Balance and gait in children with dyslexia. Exp Brain Res 150:237–244PubMedGoogle Scholar
  31. Morton SM, Bastian AJ (2004) Cerebellar control of balance and locomotion. Neuroscientist 10:247–259PubMedCrossRefGoogle Scholar
  32. Mostofsky SH, Reiss AL, Lockhart P, Denckla MB (1998) Evaluation of cerebellar size in attention-deficit hyperactivity disorder. J Child Neurol 13:434–439PubMedCrossRefGoogle Scholar
  33. Needle JL, Fawcett AJ, Nicolson RI (2006) Balance and dyslexia: an investigation of adults’ abilities. Eur J Cogn Psychol 18:909–936CrossRefGoogle Scholar
  34. Nicolson RI, Fawcett AJ (1995) Dyslexia is more than a phonological disability. Dyslexia 1:37–45Google Scholar
  35. Nicolson RI, Fawcett AJ (1997) Development of objective procedures for screening and assessment of dyslexic students in higher education. J Res Read 20:77–83CrossRefGoogle Scholar
  36. Nicolson RI, Fawcett AJ (1999) Developmental dyslexia: the role of the cerebellum. Dyslexia 5:155–177CrossRefGoogle Scholar
  37. Nicolson RI, Fawcett AJ, Dean P (1995) Time estimation deficits in developmental dyslexia: evidence for cerebellar involvement. Proc R Soc Lond Ser B 259:43–47CrossRefGoogle Scholar
  38. Nicolson RI, Fawcett AJ, Dean P (2001) Developmental dyslexia: the cerebellar deficit hypothesis. Trends Neurosci 24:508–511PubMedCrossRefGoogle Scholar
  39. Piek JP, Pitcher TM, Hay DA (1999) Motor coordination and kinaesthesis in boys with attention deficit-hyperactivity disorder. Dev Med Child Neurol 41:159–165PubMedCrossRefGoogle Scholar
  40. Raberger T, Wimmer H (2003) On the automaticity/cerebellar deficit hypothesis of dyslexia: balancing and continuous rapid naming in dyslexic and ADHD children. Neuropsychologia 41:1493–1497PubMedCrossRefGoogle Scholar
  41. Rochelle KSH, Talcott JB (2006) Impaired balance in developmental dyslexia? A meta-analysis of the contending evidence. J Child Psychol Psychiatry 77:1159–1166CrossRefGoogle Scholar
  42. Shumway-Cook A, Woollacott MH (2001) Motor control: theory and practical applications. Lippincott, Williams and Wilkins, MarylandGoogle Scholar
  43. Snowling MJ (2000) Dyslexia, 2nd edn. Blackwell, OxfordGoogle Scholar
  44. Stein J (2001) The magnocellular theory of developmental dyslexia. Dyslexia 7:12–36PubMedCrossRefGoogle Scholar
  45. Stoodley CJ, Fawcett AJ, Nicolson RI, Stein JF (2005) Impaired balancing ability in dyslexic children. Exp Brain Res 167:370–380PubMedCrossRefGoogle Scholar
  46. Voogd J (2003) The human cerebellum. J Chem Neuroanat 26:243–252PubMedCrossRefGoogle Scholar
  47. Voogd J, Glickstein M (1998) The anatomy of the cerebellum. TINS 21:370–375PubMedGoogle Scholar
  48. Wechsler D (1999) The Wechsler abbreviated scale of intelligence. The Psychological Corporation, LondonGoogle Scholar
  49. Willcutt EG, Pennington BF, Olson RK, Chhabildas N, Hulslander J (2005) Neuropsychological analyses of comorbidity between reading disability and attention deficit hyperactivity disorder: in search of the common deficit. Dev Neuropsychol 27:35–78PubMedCrossRefGoogle Scholar
  50. Wilkinson GS (1993) Wide range achievement test. Jastak Associates, WilmingtonGoogle Scholar
  51. Wimmer H, Mayringer H, Raberger T (1999) Reading and dual task balancing: evidence against the automatization deficit explanation of developmental dyslexia. J Learn Disab 32:473–478CrossRefGoogle Scholar
  52. Winter DA (2004) Biomechanics and motor control of human movement, 3rd edn. Wiley, HobokenGoogle Scholar
  53. Woollacott MH, Shumway-Cook A (2002) Attention and the control of posture and gait: a review of an emerging area of research. Gait Posture 16:1–14PubMedCrossRefGoogle Scholar
  54. Yap RL, van der Leij A (1994) Testing the automatization deficit hypothesis of dyslexia via a dual-task paradigm. J Learn Disab 27:660–665CrossRefGoogle Scholar
  55. Yardley L, Gardner M, Leadbetter A, Lavie N (1999) Effect of articulatory and mental tasks on postural control. Neuroreport 10:215–219PubMedCrossRefGoogle Scholar

Copyright information

© Springer-Verlag 2008

Authors and Affiliations

  • Kim S. H. Rochelle
    • 1
  • Caroline Witton
    • 1
  • Joel B. Talcott
    • 1
  1. 1.School of Life and Health SciencesAston UniversityBirminghamUK

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