A Bayesian model unifies multisensory spatial localization with the physiological properties of the superior colliculus
“Multisensory integration” refers to the phenomenon by which information from different senses is integrated in order to interpret and guide responses to external events. Here, we advance two specific hypotheses: (1) the process of multisensory integration in spatial localization is statistically optimal, and (2) the optimality of the processes guiding this localization results from the implementation of Bayes’ rule. We explicitly test the predictions of an optimal (Bayesian) model for the behavior of animals trained and tested in a spatial localization task, and find that the model correctly predicts behavioral patterns which are at times counterintuitive. The model also predicts the receptive field properties of superior colliculus neurons that are involved in these behaviors, and sheds new light on the computational responsibilities different circuits have in effecting these behaviors. Thus, the Bayesian model appears to represent not only a yardstick for the optimality of a behavior, but also a descriptor of the underlying neural processes.
KeywordsPrior Distribution Receptive Field Auditory Stimulus Bayesian Model Superior Colliculus
- Anastasio TJ, Patton PE (2004) Analysis and modeling of multisenosry enhancement in the deep superior colliculus. In: Calvert GA, Spence C, Stein BE (eds) The handbook of multisensory processes, Bradford Books/MIT, Cambridge, pp 265–284 Google Scholar
- Battaglia PWJRA, Aslin RN (2003) Bayesian integration of visual and auditory signals for spatial localization. J Opt Soc Am A 20(7):1391–1397Google Scholar
- Beierholm UR, Quartz SR, Shams L (2005) Bayesian inference as a unifying model of auditory–visual integration and segregation. Program No. 283.13, Abstract Viewer/Itinerary Planner. Society for Neuroscience, Washington, DC (Online)Google Scholar
- Harris LR (1980) The superior colliculus and movements of the head and eyes in cats. J Physiol (Lond) 300:367–391Google Scholar
- Stein BE, Meredith MA (1993) The merging of the senses. MIT, CambridgeGoogle Scholar