Experimental Brain Research

, Volume 167, Issue 3, pp 462–467 | Cite as

Training BIG to move faster: the application of the speed–amplitude relation as a rehabilitation strategy for people with Parkinson’s disease

Research Note


We have used the phenomenon that speed increases with movement amplitude as a rehabilitation strategy. We tested the hypothesis that the generalized training of amplitude in the limb motor system may reduce bradykinesia and hypokinesia in the upper and lower limbs in subjects with Parkinson’s disease (PD) across disease severity (Stage I, n=6; Stage II, n=7; Stage III, n=5). While studies have separately examined the relationship of amplitude to speed in reaching and gait, the same study has not reported the relationship for both limb systems. Moreover, the rehabilitation intervention, Training BIG, is unique in that it applies well-established treatment concepts from a proven treatment for the speech motor system in PD [Lee Silverman Voice Treatment (LSVT®)] to the limb motor system. Subjects (n=18) participated in intense practice (1-h sessions/4× week/4 weeks) of large amplitude movements involving the whole body (i.e., head, arm, trunk, and leg) while focusing on the sensory awareness of “movement bigness.” Testing procedures were designed to demonstrate the transfer of generalized amplitude practice to speed improvements during functional “untrained” tasks in “uncued” conditions with blinded testers. After therapy, the subjects significantly increased their speed of reaching and gait for the preferred speed condition. This effect was greater when the severity of the disease was less. The results support further application and efficacy studies of Training BIG. Amplitude-based behavioral intervention in people with PD appears to be a simple target that may be applied in different contexts for multiple tasks and results in improved speed–amplitude scaling relations across the upper and lower limbs.


Bradykinesia Reaching Gait Exercise Cueing 



This work was supported by NIH grant R21 NS043711-04A1. Statistical assistance was provided by Janet Telfer. Special thanks to Michelle Prior and Tara McIsaac for their assistance with data collection and coordination, and to all the subjects that volunteered their time to participate in this study.


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Copyright information

© Springer-Verlag 2005

Authors and Affiliations

  1. 1.Department of PhysiologyUniversity of ArizonaTucsonUSA

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