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Experimental Brain Research

, Volume 155, Issue 3, pp 393–400 | Cite as

Cortical activation following a balance disturbance

  • S. QuantEmail author
  • A. L. Adkin
  • W. R. Staines
  • W. E. McIlroy
Research Article

Abstract

Although recent work suggests that cortical processing can be involved in the control of balance responses, the central mechanisms involved in these reactions remain unclear. We presently investigated the characteristics of scalp-recorded perturbation-evoked responses (PERs) following a balance disturbance. Eight young adults stabilized an inverted pendulum using their ankle musculature while seated. When perturbations were applied to the pendulum, subjects were instructed to return (active condition) or not return (passive condition) the pendulum to its original stable position. Primary measures included peak latency and amplitude of early PERs (the first negative peak between 100 and 150 ms, N1), amplitude of late PERs (between 200 and 400 ms) and onset and initial amplitude of ankle muscle responses. Based on the timing of PERs, we hypothesized that N1 would represent sensory processing of the balance disturbance and that late PERs would be linked to the sensorimotor processing of balance corrections. Our results revealed that N1 was maximal over frontal–central electrode sites (FCz and Cz). Average N1 measures at FCz, Cz, and CPz were comparable between active and passive tasks (p>0.05). In contrast, the amplitude of late PERs at Cz was less positive for the active condition than for the passive (p<0.05). The similarity in N1 between tasks suggests a sensory representation of early PERs. Differences in late PERs may represent sensorimotor processing related to the execution of balance responses.

Keywords

Event-related potential Cortex Sensorimotor Stability 

Notes

Acknowledgements

This study was supported by the Physiotherapy Foundation of Canada (S.Q.), the Canadian Institutes of Health Research (S.Q.), and by the Natural Sciences and Engineering Research Council of Canada (W.E.M.).

References

  1. Ackermann H, Diener HC, Dichgans J (1986) Mechanically evoked cerebral potentials and long-latency muscle responses in the evaluation of afferent and efferent long-loop pathways in humans. Neurosci Lett 66:233–238CrossRefPubMedGoogle Scholar
  2. Brooke JD, Cheng J, Collins DF, McIlroy WE, Misiaszek JE, Staines WR (1997) Sensori-sensory afferent conditioning with leg movement: gain control in spinal reflex and ascending paths. Prog Neurobiol 51:393–421PubMedGoogle Scholar
  3. Cram JR, Kasman GS, Holtz J (1998) Instrumentation. In: Colilla J (ed) Introduction to surface electromyography, chapter 3. Aspen Publications, Maryland, pp 43–80Google Scholar
  4. DeVincenzo DK, Watkins S (1987) Accidental falls in a rehabilitation setting. Rehabil Nurs 12:248–252PubMedGoogle Scholar
  5. Dietz V, Quintern J, Berger W (1984a) Cerebral evoked potentials associated with the compensatory reactions following stance and gait perturbation. Neurosci Lett 50:181–186CrossRefPubMedGoogle Scholar
  6. Dietz V, Quintern J, Berger W (1984b) Corrective reactions to stumbling in man: functional significance of spinal and transcortical reflexes. Neurosci Lett 44:131–135CrossRefPubMedGoogle Scholar
  7. Dietz V, Quintern J, Berger W, Schenck E (1985a) Cerebral potentials and leg muscle e.m.g. responses associated with stance perturbation. Exp Brain Res 57:354–384Google Scholar
  8. Dietz V, Quintern J, Berger W (1985b) Afferent control of human stance and gait: evidence for blocking of group I afferents during gait. Exp Brain Res 61:53–163Google Scholar
  9. Dimitrov B, Gavrilenko T, Gatev P (1996) Mechanically evoked cerebral potentials to sudden ankle dorsiflexion in human subjects during standing. Neurosci Lett 208:199–202CrossRefPubMedGoogle Scholar
  10. Duckrow RB, Abu-Hasaballah K, Whipple R, Wolfson L (1999) Stance perturbation-evoked potentials in old people with poor gait and balance. Clin Neurophysiol 110:2026–2032CrossRefPubMedGoogle Scholar
  11. Fitzpatrick R, Rogers DK, McCloskey DI (1994) Stable human standing with lower-limb muscle afferents providing the only sensory input. J Physiol 480:395–403PubMedGoogle Scholar
  12. Hood JD, Kayan A (1985) Observations upon the evoked responses to natural vestibular stimulation. Electroencephalogr Clin Neurophysiol 62:266–276PubMedGoogle Scholar
  13. Horak FB, Macpherson JM (1996) Balance orientation and equilibrium. In: Shepard J, Rowell L (eds) Handbook of physiology. Exercise: regulation and integration of multiple systems, section 12, chapter 7. Oxford University Press, New York, pp 255–292Google Scholar
  14. Knight RT (1984) Decreased response to novel stimuli after prefrontal lesions in man. Electroencephalogr Clin Neurophysiol 59:9–20CrossRefPubMedGoogle Scholar
  15. Maki BE, Norrie RG, Zecevic A, Quant S, Kirshenbaum N, Bateni H, McIlroy WE (2001a) Initiation and execution of rapid balance reactions and stepping movements: which phases require visuospatial attention? In: Duysens J, Smits-Engelsman BCM, Kingma H (eds) Control of posture and gait. International Society for Posture and Gait Research, Maastricht, pp 573–576Google Scholar
  16. Maki BE, Zecevic A, Bateni H, Kirshenbaum N, McIlroy WE (2001b) Cognitive demands of executing balance reactions: does aging impede attention switching? Neuroreport 12:1–5PubMedGoogle Scholar
  17. Massion J (1992) Movement, posture and equilibrium interaction and coordination. Prog Neurobiol 38:35–56PubMedGoogle Scholar
  18. McIlroy WE, Norrie RG, Brooke JD, Bishop DC, Nelson AJ, Maki BE (1999) Temporal properties of attention sharing consequent to disturbed balance. Neuroreport 10:2895–2899PubMedGoogle Scholar
  19. McIlroy WE, Bishop DC, Staines WR, Nelson AJ, Maki BE, Brooke JD (2003) Modulation of afferent inflow during the control of balancing tasks using the lower limbs. Brain Res 961:73–80CrossRefPubMedGoogle Scholar
  20. Mion LC, Gregor S, Buettner M, Chwurchak D, Lee O, Paras W (1989) Falls in the rehabilitation setting: Incidence and characteristics. Rehabil Nurs 14:17–21PubMedGoogle Scholar
  21. Ouchi Y, Hiroyuki O, Yoshikawa E, Nobezawa S, Futatsubashi M (1999) Brain activation during maintenance of standing postures in humans. Brain 122:329–338CrossRefPubMedGoogle Scholar
  22. Papakostopoulos D, Cooper R, Crow HJ (1974) Cortical potentials evoked by finger displacement in man. Nature 252:582–584PubMedGoogle Scholar
  23. Quintern J, Berger W, Dietz V (1985) Compensatory reactions to gait perturbations in man: short- and long-term effects of neuronal adaptation. Neurosci Lett 62:371–376PubMedGoogle Scholar
  24. Rankin JK, Woollacott MH, Shumway-Cook A., Brown LA (2000) Cognitive influence on balance stability: a neuromuscular analysis in young and older adults. J Gerontol 55A:M112–M119Google Scholar
  25. Rapport LJ, Webster JS, Flemming KL, Lindberg JW, Godlewski MC, Brees JE, Abadee PS (1993) Predictors of falls among right-hemisphere stroke patients in the rehabilitation setting. Arch Phys Med Rehabil 74:621–626PubMedGoogle Scholar
  26. Squires NK, Squires KC, Hillyard SA (1975) Two varieties of long-latency positive waves evoked by unpredictable auditory stimuli in man. Electroencephalogr Clin Neurophysiol 38:387–401CrossRefPubMedGoogle Scholar
  27. Staines WR, McIlroy WE, Brooke JD (2001) Cortical representation of whole-body movement is modulated by proprioceptive discharge in humans. Exp Brain Res 138:235–242PubMedGoogle Scholar
  28. Starr A, McKeon B, Skuse N, Burke D (1981) Cerebral potentials evoked by muscle stretch in man. Brain 104:149–166PubMedGoogle Scholar
  29. Vlahov D, Myers AH, Al-Ibrahim MS (1990) Epidemiology of falls among patients in a rehabilitation hospital. Arch Phys Med Rehabil 71:8–12PubMedGoogle Scholar

Copyright information

© Springer-Verlag 2004

Authors and Affiliations

  • S. Quant
    • 1
    • 2
    Email author
  • A. L. Adkin
    • 3
    • 5
  • W. R. Staines
    • 4
    • 6
  • W. E. McIlroy
    • 1
    • 2
    • 3
    • 4
    • 5
  1. 1.Institute of Medical ScienceUniversity of TorontoTorontoCanada
  2. 2.Department of Physical Therapy, Faculty of MedicineUniversity of TorontoTorontoCanada
  3. 3.Graduate Department of Rehabilitation ScienceUniversity of TorontoTorontoCanada
  4. 4.Department of Medicine (Neurology)University of TorontoTorontoCanada
  5. 5.Restorative Motor Control LaboratoryToronto Rehabilitation InstituteTorontoCanada
  6. 6.Department of Kinesiology and Health ScienceYork UniversityTorontoCanada

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