Experimental Brain Research

, Volume 153, Issue 2, pp 180–189 | Cite as

Visually guided grasping produces fMRI activation in dorsal but not ventral stream brain areas

  • Jody C. Culham
  • Stacey L. Danckert
  • Joseph F. X. De Souza
  • Joseph S. Gati
  • Ravi S. Menon
  • Melvyn A. Goodale
Research Article

Abstract

Although both reaching and grasping require transporting the hand to the object location, only grasping also requires processing of object shape, size and orientation to preshape the hand. Behavioural and neuropsychological evidence suggests that the object processing required for grasping relies on different neural substrates from those mediating object recognition. Specifically, whereas object recognition is believed to rely on structures in the ventral (occipitotemporal) stream, object grasping appears to rely on structures in the dorsal (occipitoparietal) stream. We used functional magnetic resonance imaging (fMRI) to determine whether grasping (compared to reaching) produced activation in dorsal areas, ventral areas, or both. We found greater activity for grasping than reaching in several regions, including anterior intraparietal (AIP) cortex. We also performed a standard object perception localizer (comparing intact vs. scrambled 2D object images) in the same subjects to identify the lateral occipital complex (LOC), a ventral stream area believed to play a critical role in object recognition. Although LOC was activated by the objects presented on both grasping and reaching trials, there was no greater activity for grasping compared to reaching. These results suggest that dorsal areas, including AIP, but not ventral areas such as LOC, play a fundamental role in computing object properties during grasping.

Keywords

fMRI Grasping Reaching Visuomotor control Parietal cortex 

Notes

Acknowledgements

These projects would not have been possible without the engineering skills needed to design the apparatus. We are especially grateful to Dave Woytowich and Bob Stuart at UWO Engineering Machine Shops for designing and building the grasparatus, to Dan Pulham for wiring the electronics, to Leopold van Cleeff and Derek Quinlan for developing other hardware, and to Raynald Comtois for programming the input/output card. Philip Servos provided the air compressor and solenoids and assistance with their use. Zoe Kourtzi generously provided the object stimuli and Matlab code to present them. These experiments were supported by grants from the McDonnell-Pew Program in Cognitive Neuroscience (to JCC), the Canadian Institutes of Health Research (Operating Grant to MAG and NSERC/CIHR Multi-User Maintenance grant to RSM and colleagues), and the Canada Research Chairs Program (to MAG and RSM).

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Copyright information

© Springer-Verlag 2003

Authors and Affiliations

  • Jody C. Culham
    • 1
  • Stacey L. Danckert
    • 1
  • Joseph F. X. De Souza
    • 1
    • 2
  • Joseph S. Gati
    • 3
  • Ravi S. Menon
    • 3
  • Melvyn A. Goodale
    • 1
  1. 1.Department of PsychologyUniversity of Western OntarioLondonCanada
  2. 2.Department of PhysiologyUniversity of Western OntarioLondonCanada
  3. 3.Advanced Imaging LabsJohn P. Robarts Research InstituteLondonCanada

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