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European Food Research and Technology

, Volume 238, Issue 3, pp 409–416 | Cite as

Health-promoting effects in the gut and influence on lipid metabolism of Himanthalia elongata and Gigartina pistillata in hypercholesterolaemic Wistar rats

  • María-José Villanueva
  • Mónica Morcillo
  • María-Dolores Tenorio
  • Inmaculada Mateos-AparicioEmail author
  • Víctor Andrés
  • Araceli Redondo-Cuenca
Original Paper

Abstract

The intake of Himanthalia elongata and Gigartina pistillata from the Spanish Atlantic coasts was evaluated in Wistar rats. Both seaweed diets showed higher (p < 0.001) faecal excretion. Colonic fermentation increased (p < 0.001) total short-chain fatty acids (SCFAs) in Himanthalia-fed rats due to the higher (p < 0.001) levels of acetic, propionic and butyric acids. The intake of Gigartina increased (p < 0.001) propionic acid and decreased (p < 0.001) butyric acid. The apparent absorption and true retention of calcium and magnesium enhanced (p < 0.05) with Himanthalia diet, while Gigartina produced no significant effect. The serum concentration of HDL-C increased (p < 0.01), triglycerides (TGL) decreased (p < 0.001) and bile acids diminished (p < 0.001) in faeces of Himanthalia-fed rats. The Gigartina diet produced a decrease (p < 0.001) in TGL, total cholesterol (p < 0.01) and LDL-C (p < 0.05) in serum and reduced TGL in liver (p < 0.001). Thus, both seaweeds improved the lipid profile, and Himanthalia increased SCFA production and the absorption and retention of Ca and Mg as a result of the gut fermentation.

Keywords

Edible seaweeds Dietary fibre Prebiotic Mineral balance Cholesterol Lipid profile 

Notes

Acknowledgments

This research work was supported by the Spanish Ministerio de Ciencia e Innovación, through Project AGL2008-00998 ALI. Thanks are given to the algal supplier Porto-Muiños (Coruña, Spain).

Conflict of interest

None.

Compliance with Ethics Requirements

This article does not contain any studies with human or animal subjects.

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Copyright information

© Springer-Verlag Berlin Heidelberg 2013

Authors and Affiliations

  • María-José Villanueva
    • 1
  • Mónica Morcillo
    • 1
  • María-Dolores Tenorio
    • 1
  • Inmaculada Mateos-Aparicio
    • 1
    Email author
  • Víctor Andrés
    • 1
  • Araceli Redondo-Cuenca
    • 1
  1. 1.Dpto. Nutrición y Bromatología II, Facultad de FarmaciaUniversidad Complutense de MadridMadridSpain

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