Fresenius' Journal of Analytical Chemistry

, Volume 362, Issue 6, pp 529–536

Determination of the plasticizer N-butylbenzenesulfonamide and the pharmaceutical Ibuprofen in wastewater using solid phase microextraction (SPME)

  • N. Huppert
  • Marion Würtele
  • Hermann H. Hahn
Original paper

DOI: 10.1007/s002160051119

Cite this article as:
Huppert, N., Würtele, M. & Hahn, H. Fresenius J Anal Chem (1998) 362: 529. doi:10.1007/s002160051119

Abstract

A rapid, inexpensive and solvent-free method for the simultaneous determination of the polyamide plasticizer N-butylbenzenesulfonamide (NBBS) and the widely used pharmaceutical Ibuprofen by solid phase microextraction (SPME) combined with gas chromatography/mass spectrometry (GC/MSD) in wastewater samples was developed. Besides the optimized analytical conditions, results of investigations with varying analytical parameters are reported. Problems, which may occur during the analytical procedure (e.g. salt deposits, adsorption phenomena, carry-over), are discussed. For the determination of Ibuprofen, it is important to carry out the extraction under acidic conditions with sufficiently buffered samples; the GC/MSD system must be very clean and well maintained. SPME allows an extraction of Ibuprofen without derivatization of its carboxylic group. For quantification in complex matrices, the standard addition technique is necessary. Limit of detection and limit of determination are 0.1 μg/L for both analytes. NBBS and Ibuprofen were detected in several raw and treated wastewater samples from municipal wastewater treatment plants in the range from < 0.1 to 3.5 μg/L.

Copyright information

© Springer-Verlag Berlin Heidelberg 1998

Authors and Affiliations

  • N. Huppert
    • 1
  • Marion Würtele
    • 1
  • Hermann H. Hahn
    • 1
  1. 1.Institute for Aquatic Environmental Engineering, University of Karlsruhe, Am Fasanengarten, D-76128 Karlsruhe, GermanyDE

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