Fresenius' Journal of Analytical Chemistry

, Volume 368, Issue 4, pp 429–431 | Cite as

A flow injection chemiluminescence system for the determination of isoniazid

  • Y. Huang
  • Z. Zhang
  • D. Zhang
  • J. Lv
Short communication

Abstract

A chemiluminescence (CL) flow system is described for the determination of isoniazid based on its enhancement on the chemiluminescence (CL) emission produced upon mixing a hexacyanoferrate(III) solution with an alkaline luminol solution. The system responds linearly to isoniazid concentration in the range 0–1 mg/L with a detection limit (3σ) of 0.03 μg/L, relative standard deviation (RSD) of 1.2% for 0.1 mg/L isoniazid (n = 11). The system has been successfully applied to the determination of isoniazid in pharmaceutical preparations.

Keywords

Standard Deviation Detection Limit Relative Standard Deviation Isoniazid Flow System 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.
This is a preview of subscription content, log in to check access.

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

Copyright information

© Springer-Verlag Berlin Heidelberg 2000

Authors and Affiliations

  • Y. Huang
    • 1
  • Z. Zhang
    • 1
  • D. Zhang
    • 2
  • J. Lv
    • 3
  1. 1.Institute of Analytical Sciences, Southwest Normal University, Beibei, Chongqing 400715, P.R.ChinaCN
  2. 2.Department of Chemistry, Southwest Normal University, Beibei, Chongqing 400715, P.R.ChinaCN
  3. 3.Department of Chemistry, Shaanxi Normal University, Xi’an 710062, P. R. ChinaCN

Personalised recommendations