β-Cyclodextrin molecularly imprinted solid-phase microextraction coatings for selective recognition of polychlorophenols in water samples
- 214 Downloads
A series of β-cyclodextrin derivatives were designed and synthesized. The derivatives were investigated as functional monomers in molecularly imprinted polymeric solid-phase microextraction (MIP-SPME) fiber coatings. The coatings, with a layer thickness of 250 μm, were immobilized onto stainless steel using a capillary tube as a mold. This study employed a simple, easy, and reproducible method to prepare uniform coatings for polychlorophenols extraction. The combination of molecular inclusion effects and the molecular imprinting sites was expected to enhance the molecular recognition ability for polychlorophenols. Compared with non-imprinted polymer coatings and MIP coatings with methacrylic acid as the functional monomer, the β-cyclodextrin MIP-SPME coatings exhibited significantly higher extraction amounts and excellent selectivity to the template of triclosan. The MIP-SPME coatings exhibited a favorable synergistic extraction capacity resulting from the β-cyclodextrin cavity and molecularly imprinted binding sites. The method of β-cyclodextrin MIP-SPME coupled with high performance liquid chromatography (HPLC) for triclosan and polychlorophenols analysis in real water samples was developed. The limit of quantification was 1 μg/L for the three polychlorophenols. The recovery for three analytes ranged from 83.71% to 109.98%, with the relative standard deviation (RSD) of 2.83% to 12.19%. The β-cyclodextrin MIP-SPME fiber coatings could be used for at least 100 cycles.
KeywordsMolecularly imprinted polymer Solid-phase microextraction β-Cyclodextrin Synergistic effects Polychlorophenols
This work is supported by the National Natural Science Foundation of China (21565018).
Compliance with ethical standards
Conflict of interest
The authors declare that they have no conflict of interest.
- 7.Turiel E, Tadeo JL, Martínesteban A. Molecularly imprinted polymeric fibers for solid-phase microextraction. Anal Chem. 2009;32(19):3278–84.Google Scholar
- 10.Surikumaran H, Mohamad S, Sarih NM, Raoov M. β-Cyclodextrin based molecularly imprinted solid phase extraction for class selective extraction of priority phenols in water. Sep Sci Technol. 2015;50:2342–51.Google Scholar
- 14.Zhang Y, Li YW, Hu YL, Li GK, Chen YQ. Preparation of magnetic indole-3-acetic acid imprinted polymer beads with 4-vinylpyridine and β-cyclodextrin as binary monomer via microwave heating initiated polymerization and their application to trace analysis of auxins in plant tissues. J Chromatogr A. 2010;217(47):7337–44.CrossRefGoogle Scholar
- 27.Michalowicz J, Duda W. Phenols sources and toxicity. Pol J Environ Stud. 2007;16:347–62.Google Scholar
- 31.EC Drinking Water Guideline, 98/83/CE, November (1998) European Union, BrusselsGoogle Scholar
- 32.Federal Register, EPA method 604, Phenols, Part VIII, 40 CFR Part 136, Washington (1984) US Environmental Protection Agency (EPA)Google Scholar