Analytical and Bioanalytical Chemistry

, Volume 410, Issue 3, pp 747–771 | Cite as

Bioinspired recognition elements for mycotoxin sensors

  • Riikka Peltomaa
  • Elena Benito-Peña
  • María C. Moreno-BondiEmail author
Part of the following topical collections:
  1. ABCs 16th Anniversary


Mycotoxins are low molecular weight molecules produced as secondary metabolites by filamentous fungi that can be found as natural contaminants in many foods and feeds. These toxins have been shown to have adverse effects on both human and animal health, and are the cause of significant economic losses worldwide. Sensors for mycotoxin analysis have traditionally applied elements of biological origin for the selective recognition purposes. However, since the 1970s there has been an exponential growth in the use of genetically engineered or synthetic biomimetic recognition elements that allow some of the limitations associated with the use of natural receptors for the analyses of these toxins to be circumvented. This review provides an overview of recent advances in the application of bioinspired recognition elements, including recombinant antibodies, peptides, aptamers, and molecularly imprinted polymers, to the development of sensors for mycotoxins based on different transduction elements.

Graphical abstract

Novel analytical methods based on bioinspired recognition elements, such as recombinant antibodies, peptides, aptamers, and molecularly imprinted polymers, can improve the detection of mycotoxins and provide better tools than their natural counterparts to ensure food safety


Mycotoxin Recognition element Recombinant antibody Peptide Aptamer Molecularly imprinted polymer 



This work was funded by the European Union (SAMOSS; FP7-PEOPLE-2013-ITN; contract 607590) and MINECO/FEDER (CTQ2015-69278-C2-1-R).

Compliance with ethical standards

Conflict of interest

The authors declare that they have no competing interests.


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Copyright information

© Springer-Verlag GmbH Germany 2017

Authors and Affiliations

  • Riikka Peltomaa
    • 1
  • Elena Benito-Peña
    • 1
  • María C. Moreno-Bondi
    • 1
    Email author
  1. 1.Department of Analytical Chemistry, Faculty of ChemistryUniversidad Complutense de MadridMadridSpain

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