Analytical and Bioanalytical Chemistry

, Volume 408, Issue 25, pp 6913–6927 | Cite as

Recent advances and progress in the detection of bisphenol A

  • Fengxia Sun
  • Lichao Kang
  • Xiaoli Xiang
  • Hongmin Li
  • Xiaoling Luo
  • Ruifeng Luo
  • Chunxia Lu
  • Xiayu PengEmail author


Bisphenol A (BPA) is an important industrial chemical used as a plasticizer in polycarbonate and epoxy resins in the plastic and paper industries. Because of its estrogenic properties, BPA has attracted increasing attention from many researchers. This review focuses primarily on analytical methods for BPA detection that have emerged in recent years. We present and discuss the advantages and disadvantages of sample preparation techniques (e.g., solvent extraction, solid-phase extraction, molecularly imprinted polymer solid-phase extraction, and micro-extraction techniques) and analytical methods (e.g., liquid chromatography, liquid chromatography−mass spectrometry, gas chromatography−mass spectrometry, capillary electrophoresis, immunoassay, and several novel sensors). We also discuss expected future developments for the detection of BPA.

Graphical Abstract

This review focuses primarily on the recent development in the detection of bisphenol A including sample pre-treatment and analytical methods


Bisphenol A Sample pretreatment Mass spectrometry Immunoassay Sensors Molecularly imprinted polymers 



The authors acknowledge financial support from the National Natural Science Foundation of China (no. 21567027), the Scientific and Technological Project of the XPCC (no. 2015AB009), and the Science & Technology to guide project of Xinjiang Academy of Agriculture and Reclamation Science (no. 76YYD201501).

Compliance with Ethical Standards

Conflict of interest

The authors declare that they have no conflict of interest.


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Copyright information

© Springer-Verlag Berlin Heidelberg 2016

Authors and Affiliations

  • Fengxia Sun
    • 1
    • 2
  • Lichao Kang
    • 1
  • Xiaoli Xiang
    • 1
  • Hongmin Li
    • 1
  • Xiaoling Luo
    • 1
    • 2
  • Ruifeng Luo
    • 1
  • Chunxia Lu
    • 1
  • Xiayu Peng
    • 2
    Email author
  1. 1.Analysis and Testing CenterXinjiang Academy of Agriculture and Reclamation ScienceShiheziChina
  2. 2.State Key Laboratory of Sheep Genetic Improvement & Healthy BreedingXinjiang Academy of Agriculture and Reclamation ScienceShiheziChina

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