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Analytical and Bioanalytical Chemistry

, Volume 408, Issue 7, pp 1727–1733 | Cite as

Molecularly imprinted polymers with multi-functionality

Trends
Part of the following topical collections:
  1. Analytical Applications of Biomimetic Recognition Elements

Abstract

Molecular imprinting is a very powerful synthetic method for preparation of robust materials with pre-designed molecular selectivity. Molecularly imprinted polymers (MIPs) are attractive substitutes for antibodies in many analytical and bioanalytical applications, e.g. for development of biosensors and for drug assays. In addition to selective molecular binding, new functions are being added to MIPs to make the synthetic materials responsive to different environmental conditions, making it possible to modulate the binding and release of different molecular targets and to simplify affinity separation. Introduction of signal-transduction functionality into MIPs also brings in new, more easily operated chemical sensors for detection and quantification of important analytical targets.

Graphical Abstract

Multi-functional molecularly imprinted polymers

Keywords

Molecular imprinting Multi-functionality Nanoparticle Composite material Controlled radical polymerization 

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Copyright information

© Springer-Verlag Berlin Heidelberg 2015

Authors and Affiliations

  1. 1.Division of Pure and Applied BiochemistryLund UniversityLundSweden

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