Analytical and Bioanalytical Chemistry

, Volume 407, Issue 10, pp 2711–2726 | Cite as

A review of biosensing techniques for detection of trace carcinogen contamination in food products

  • Zhanming Li
  • Yue Yu
  • Zhiliang Li
  • Tao WuEmail author


Carcinogen contaminations in the food chain, for example heavy metal ions, pesticides, acrylamide, and mycotoxins, have caused serious health problems. A major objective of food-safety research is the identification and prevention of exposure to these carcinogens, because of their impossible-to-reverse tumorigenic effects. However, carcinogen detection is difficult because of their trace-level presence in food. Thus, reliable and accurate separation and determination methods are essential to protect food safety and human health. This paper summarizes the state of the art in separation and determination methods for analyzing carcinogen contamination, especially the advances in biosensing methods. Furthermore, the application of promising technology including nanomaterials, imprinted polymers, and microdevices is detailed. Challenges and perspectives are also discussed.


Carcinogen Separation Determination Biosensing Nanomaterial Microfluidic 



The research was supported by Project of the Ministry of Science and Technology of the People’s Republic of China (No. 2012BAD33B08).

Conflict of interest

The authors declare that they have no conflict of interest.


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Copyright information

© Springer-Verlag Berlin Heidelberg 2015

Authors and Affiliations

  1. 1.Department of Biosystems EngineeringZhejiang UniversityHangzhouChina
  2. 2.Department of ChemistryUniversity of FloridaGainesvilleUSA
  3. 3.Department of Food Science and NutritionZhejiang UniversityHangzhouChina
  4. 4.Key Laboratory of Food Nutrition and Safety (Tianjin University of Science & Technology), Ministry of EducationTianjinChina

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