Analytical and Bioanalytical Chemistry

, Volume 403, Issue 3, pp 867–876 | Cite as

On-line solid-phase extraction coupled to ultra-performance liquid chromatography with tandem mass spectrometry detection for the determination of benzotriazole UV stabilizers in coastal marine and wastewater samples

  • Sarah Montesdeoca-Esponda
  • Zoraida Sosa-Ferrera
  • José Juan Santana-Rodríguez
Original Paper

Abstract

Benzotriazoles are a group of UV absorbing compounds considered emerging contaminants that are used in different personal care products, and therefore, it is of high interest to develop sensitive and fast methods for investigating their presence in the environment. In this work, we present the development and application of a novel method based on on-line solid-phase extraction coupled to ultra-performance liquid chromatography with tandem mass spectrometry detection (SPE-UPLC-MS/MS) for the determination of seven benzotriazole UV stabilizers (BUVSs) in coastal marine and wastewater samples. This process is compared with a conventional off-line SPE procedure followed by UPLC-MS/MS. The parameters affecting the performance of the sample preparation and determination processes were evaluated. The results indicate that the on-line procedure provides for better sensitivity and reproducibility and is faster and easier than the off-line procedure. The detection limits and quantification limits achieved were in the range of 0.6–4.1 ng∙L−1 and 2.1–14 ng∙L−1 and relative standard deviation between 6.2 and 10 %. The developed method was applied to coastal marine and wastewater samples from Gran Canaria Island (Spain). All of the BUVSs studied were detected in the samples from wastewater treatment plants and two were found in the seawater samples (UV P in the range of 2.8–4.4 ng∙L−1 and UV 360 between 3.6 and 5.2 ng∙L−1).

Keywords

Benzotriazole UV stabilizers On-line SPE UPLC-MS/MS Water analysis 

References

  1. 1.
    Richardson SD (2008) Anal Chem 80:4373–4402CrossRefGoogle Scholar
  2. 2.
    Reemtsma T, Quintana JB, Rodel R, García-López M, Rodríguez I (2008) Trends Anal Chem 27:727–737CrossRefGoogle Scholar
  3. 3.
    Hernando MD, Mezcua M, Fernandez-Alba AR, Barceló D (2006) Talanta 69:334–342CrossRefGoogle Scholar
  4. 4.
    Zhou Y, Huang SX, Pu JX, Li JR, Ding LS, Chen DF, Sun HD, Xu HX (2011) J Pharm Biom Anal 56:916–927CrossRefGoogle Scholar
  5. 5.
    Qin L, Liu F, Wu H, Zhu G (2012) Adv Mater Res 343:855–861CrossRefGoogle Scholar
  6. 6.
    Klapoetke SC, Zhang J, Becht S (2011) J Pharm Biom Anal 56:513–520CrossRefGoogle Scholar
  7. 7.
    Pedrouzo M, Borrull F, Marcé RM, Pocurull E (2009) J Chromatogr A 1216:6994–7000CrossRefGoogle Scholar
  8. 8.
    Gosetti F, Chiuminatto U, Mazzucco E, Robotti E, Calabrese G, Gennaro MC, Marengo E (2011) J Chromatogr A 1218:6308–6318CrossRefGoogle Scholar
  9. 9.
    Gosetti F, Chiuminatto U, Zampieri D, Mazzucco E, Robotti E, Calabrese G, Gennaro MC, Marengo E (2010) J Chromatogr A 1217:7864–7872CrossRefGoogle Scholar
  10. 10.
    Chiuminatto U, Gosetti F, Dossetto P, Mazzucco E, Zampieri D, Robotti E, Gennaro MC, Marengo E (2010) Anal Chem 82:5636–5645CrossRefGoogle Scholar
  11. 11.
    Ismaiel OA, Zhang T, Jenkins R, Karnes HT (2011) J Chromatogr B 879:2081–2088CrossRefGoogle Scholar
  12. 12.
    López-Roldán R, de Alda ML, Gros M, Petrovic M, Martín-Alonso J, Barceló D (2010) Chemosphere 80:1337–1344CrossRefGoogle Scholar
  13. 13.
    Shen J, Guo L, Xu F, Rao Q, Xia X, Li X, Ding S (2010) Chromatographia 71:383–388CrossRefGoogle Scholar
  14. 14.
    Baker DR, Kasprzyk-Hordern B (2011) J Chromatogr A 1218:1620–1631CrossRefGoogle Scholar
  15. 15.
    Nakata H, Murata S, Filatreau J (2009) J Environ Sci Technol 43:6920–6926CrossRefGoogle Scholar
  16. 16.
    Niklasson B, Bjorkner B (1989) Contact dermatitis 21:330–334CrossRefGoogle Scholar
  17. 17.
    Morohoshi K, Yamamoto H, Kamata R, Shiraishi F, Koda T, Morita M (2005) Toxicol Vitr 19:457–469CrossRefGoogle Scholar
  18. 18.
    Kawamura Y, Ogawa Y, Nishimura T, Kikuchi Y, Nishikawa J, Nishihara T, Tanamoto K (2003) J Health Sci 49:205–212CrossRefGoogle Scholar
  19. 19.
    La Farré M, Pérez S, Kantiani L, Barcelo D (2008) Trends Anal Chem 27:991–1007CrossRefGoogle Scholar
  20. 20.
    Council Directive of 27 July 1976 on the approximation of the laws of the Member States relating to cosmetic products (76/768/EEC)Google Scholar
  21. 21.
  22. 22.
  23. 23.
  24. 24.
    Nakata H, Murata S, Shinohara R, Filatreau J, Isobe T, Takahashi S, Tanabe S (2009) Interdisciplinary Studies on environmental chemistry-environmental research in Asia 239–246Google Scholar
  25. 25.
    Kim JW, Ramaswamy BR, Chang KH, Isobe T, Tanabe S (2011) J Chromatogr A 1218:3511–3520CrossRefGoogle Scholar
  26. 26.
    Nakata H, Shinohara R, Murata S, Watanabe M (2010) J Environ Monit 12:2088–2092CrossRefGoogle Scholar
  27. 27.
    Reddy CM, Quinn JG, King JW (2000) Environ Sci Technol 34:973–979CrossRefGoogle Scholar
  28. 28.
    Kameda Y, Kimura K, Miyazaki M (2011) Env Poll 159:1570–1576CrossRefGoogle Scholar
  29. 29.
    Zhang Z, Ren N, Li Y, Kunisue T, Gao D, Kannan K (2011) Environ Sci Technol 45:3909–3916Google Scholar
  30. 30.
    Carpinteiro I, Abuín B, Rodríguez I, Cela R, Ramil M (2010) Anal Bioanal Chem 397:829–839CrossRefGoogle Scholar
  31. 31.
    Mallet C, Shah D (2010) UPLC with on-line SPE technology for the analysis of pesticides and pharmaceuticals in drinking water. Application Note of Waters Corporation. Waters, Milford, MA USAGoogle Scholar
  32. 32.
  33. 33.
    US EPA (2011). Estimation Programs Interface Suite™ v4.10. United States Environmental Protection Agency, Washington, DC, USAGoogle Scholar

Copyright information

© Springer-Verlag 2012

Authors and Affiliations

  • Sarah Montesdeoca-Esponda
    • 1
  • Zoraida Sosa-Ferrera
    • 1
  • José Juan Santana-Rodríguez
    • 1
  1. 1.Departamento de QuímicaUniversidad de Las Palmas de Gran CanariaLas Palmas de Gran CanariaSpain

Personalised recommendations