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Analytical and Bioanalytical Chemistry

, Volume 403, Issue 8, pp 2411–2418 | Cite as

Solid-phase microextraction of 2,4,6-trinitrotoluene using a molecularly imprinted-based fiber

  • Federica BianchiEmail author
  • Marco GiannettoEmail author
  • G. Mori
  • G. D’Agostino
  • M. Careri
  • A. Mangia
Original Paper

Abstract

A molecularly imprinted polymer with trinitrotoluene as the template molecule was synthesized and used as the novel coating for solid-phase microextraction of the nitroaromatic explosive 2,4,6-trinitrotoluene for its selective determination. The fiber was characterized in terms of coating thickness, morphology, intra- and inter-batch repeatability and extraction efficiency. An average thickness of 50 ± 4 μm with a uniform distribution of the coating was obtained. Good performances of the developed procedure in term of both intra-batch and inter-batch repeatability with relative standard deviations <8% were obtained. Finally, detection and quantitation limits in the low nanogram per kilogram levels were achieved proving the superior extraction capability of the developed coating, obtaining gas chromatography-mass spectrometry responses about two times higher than those achieved using commercial devices.

Figure

Preparation of a MIP-based fiber for the solid-phase microextraction of 2,4,6-trinitrotoluene

Keywords

Solid-phase microextraction Molecularly imprinted polymer 2,4,6-Trinitrotoluene Coating Explosives 

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Copyright information

© Springer-Verlag 2012

Authors and Affiliations

  1. 1.Dipartimento di Chimica Generale ed Inorganica, Chimica Analitica, Chimica FisicaUniversità degli Studi di ParmaParmaItaly
  2. 2.EUROFOS-European Master Course in Forensic SciencesParmaItaly
  3. 3.Dipartimento di Chimica GeneraleUniversità degli Studi di PaviaPaviaItaly

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