Analytical and Bioanalytical Chemistry

, Volume 397, Issue 5, pp 1673–1681

Biological methods for marine toxin detection

  • Natalia Vilariño
  • M. Carmen Louzao
  • Mercedes R. Vieytes
  • Luis M. Botana
Review

Abstract

The presence of marine toxins in seafood poses a health risk to human consumers which has prompted the regulation of the maximum content of marine toxins in seafood in the legislations of many countries. Most marine toxin groups are detected by animal bioassays worldwide. Although this method has well known ethical and technical drawbacks, it is the official detection method for all regulated phycotoxins except domoic acid. Much effort by the scientific and regulatory communities has been focused on the development of alternative techniques that enable the substitution or reduction of bioassays; some of these have recently been included in the official detection method list. During the last two decades several biological methods including use of biosensors have been adapted for detection of marine toxins. The main advances in marine toxin detection using this kind of technique are reviewed. Biological methods offer interesting possibilities for reduction of the number of biosassays and a very promising future of new developments.

Keywords

Phycotoxin Seafood Shellfish poisoning Biosensor SPR 

Copyright information

© Springer-Verlag 2010

Authors and Affiliations

  • Natalia Vilariño
    • 1
  • M. Carmen Louzao
    • 1
  • Mercedes R. Vieytes
    • 2
  • Luis M. Botana
    • 1
  1. 1.Departamento de Farmacología, Facultad de VeterinariaUniversidad de Santiago de Compostela, Campus UniversitarioLugoSpain
  2. 2.Departamento de Fisiología, Facultad de VeterinariaUniversidad de Santiago de Compostela, Campus UniversitarioLugoSpain

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