Trends in Fourier transform infrared spectroscopic imaging
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Fourier transform infrared (FTIR) spectroscopic imaging is a relatively new method that has received great attention as a new field of analytical chemistry. The greatest benefit of this technique lies in the high molecular sensitivity combined with a spatial resolution down to a few micrometers. Another advantage is the ability to probe samples under native conditions, which allows new insights into samples without the need for fixation, stains, or an additional marker. Advances in instrumentation have made FTIR spectroscopic imaging the tool of choice for an increasing number of applications. The main applications are in the bioanalytical chemistry of cells and tissue, polymers, and recently as well as in homeland security. This report gives a short overview of current developments and recent applications.
KeywordsFourier transform infrared imaging spectroscopy Biomedical applications Polymer analysis High-throughput analysis Analysis of plants
The author would like thank Reiner Salzer (Department of Chemistry, Dresden University of Technology,) for his help and advice. We thank Stephan Sobottka (Department of Neurosurgery, Dresden University of Technology) for providing the MRI and brain tissue samples. The working groups of Karl Friedrich Arndt (Department of Chemistry, Dresden University of Technology,) and Gerald Gerlach (Institute for Solid-State Electronics, Dresden University of Technology) are gratefully acknowledged for preparing the polymer samples. We would also like to acknowledge Frank Koschine from Bruker Optik GmbH for his support and information.
- 2.Grahn HF, Geladi P (eds) (2007) Techniques and applications of hyperspectral image analysis. Wiley, New YorkGoogle Scholar
- 13.Diem M, Griffiths P, Chalmers J (2008) Vibrational spectroscopy for medical diagnosis. Wiley, New YorkGoogle Scholar