Advertisement

Recent advances in the development of novel materials for mycotoxin analysis

  • Chris M. MaragosEmail author
Review

Abstract

For sensitive and specific toxin detection, mycotoxin immunoassays depend upon antibodies with high affinity and selectivity. While intact immunoglobulins remain the primary toxin-binding elements used in rapid assays, a number of alternatives have begun appearing in the literature. The alternatives can be broadly classified into those that are obtained by chemical synthesis and those that are obtained by altering biologically derived materials. Examples range from synthetically prepared polymers to recombinant fragments of antibodies, with a wide variety of synthetic and natural materials in-between. To date, obtaining the combination of selectivity and affinity needed for use in sensors has been more readily accomplished with biologically derived materials than with synthetic materials. Despite this, synthetic materials still offer certain potential advantages, such as high binding capacity and the ability to bind in environments that are too harsh for intact antibodies. This review focuses upon recent advances in the development of mycotoxin-binding materials and their potential for application in mycotoxin assays.

Keywords

Mycotoxin analysis Antibody Polymer Aptamer Cyclodextrins Binding materials 

Notes

Disclaimer

Mention of trade names or commercial products in this article is solely for the purpose of providing specific information and does not imply recommendation or endorsement by the US Department of Agriculture.

References

  1. 1.
    Maragos CM (2009) World Mycotoxin J. doi: 10.3920/WMJ2008.1117
  2. 2.
    Shephard GS (2008) J AOAC Int 91:1B–16BGoogle Scholar
  3. 3.
    Shephard GS (2008) Chem Soc Rev 37:2468–2477CrossRefGoogle Scholar
  4. 4.
    Krska R, Schubert-Ullrich P, Molinelli A, Sulyok M, MacDonald S, Crews C (2008) Food Addit Contam 25:152–163CrossRefGoogle Scholar
  5. 5.
    De Saeger S, Sibanda L, Paepens C, Lobeau M, Delmulle B, Barna-Vetro I, Van Peteghem C (2008) Mycotoxin Res 22:100–104CrossRefGoogle Scholar
  6. 6.
    Logrieco A, Arrigan DWM, Brengel-Pesce K, Siciliano P, Tothill I (2005) Food Addit Contam 22:335–344CrossRefGoogle Scholar
  7. 7.
    Prieto-Simon B, Noguer T, Campas M (2007) Trends Anal Chem 26:689–702CrossRefGoogle Scholar
  8. 8.
    Wark KL, Hudson PJ (2006) Adv Drug Deliv Rev 58:657–670CrossRefGoogle Scholar
  9. 9.
    Yuan Q, Clarke JR, Zhou HR, Linz JE, Pestka JJ, Hart LP (1997) Appl Environ Microbiol 63:263–269Google Scholar
  10. 10.
    Chang HJ, Choi SW, Chun H (2008) Biotechnol Lett 30:1801–1806CrossRefGoogle Scholar
  11. 11.
    Wang SH, Du XY, Lin L, Huang YM, Wang ZH (2008) World J Microbiol Biotechnol 24:1681–1685CrossRefGoogle Scholar
  12. 12.
    Moghaddam A, Lobersli I, Gebhardt K, Braunagel M, Marvik OJ (2001) J Immunol Methods 254:169–181CrossRefGoogle Scholar
  13. 13.
    Daly S, Dillon P, Manning B, Dunne L, Killard A, O’Kennedy R (2002) Food Agric Immunol 14:255–274CrossRefGoogle Scholar
  14. 14.
    Dunne L, Daly S, Baxter A, Haughey S, O’Kennedy R (2005) Spectrosc Lett 38:229–245CrossRefGoogle Scholar
  15. 15.
    Choi GH, Lee DH, Min WK, Cho YJ, Kweon DH, Son DH, Park K, Seo JH (2004) Protein Expr Purif 35:84–92CrossRefGoogle Scholar
  16. 16.
    Wang SH, Du XY, Huang YM, Lin DS, Hart LP, Wang ZH (2007) FEMS Microbiol Lett 272:214–219CrossRefGoogle Scholar
  17. 17.
    Zhou HR, Pestka JJ, Hart LP (1996) J Food Prot 59:1208–1212Google Scholar
  18. 18.
    Lauer B, Ottleben I, Jacobsen HJ, Reinard T (2005) J Agric Food Chem 53:899–904CrossRefGoogle Scholar
  19. 19.
    Yuan Q, Hu W, Pestka JJ, He SY, Hart LP (2000) Appl Environ Microbiol 66:3499–3505CrossRefGoogle Scholar
  20. 20.
    Peschen D, Li HP, Fischer R, Kreuzaler F, Liao YC (2004) Nat Biotechnol 22:732–738CrossRefGoogle Scholar
  21. 21.
    Yuan Q, Pestka JJ, Hespenheide BM, Kuhn LA, Linz JE, Hart LP (1999) Appl Environ Microbiol 65:3279–3286Google Scholar
  22. 22.
    Liu R, Yu Z, He Q, Xu Y (2007) Food Control 18:872–877CrossRefGoogle Scholar
  23. 23.
    Hamers-Casterman C, Atarhouch T, Muyldermans S, Robinson G, Hamers C, Bajyana Songa E, Bendahman N, Hamers R (1993) Nature 363:446–448CrossRefGoogle Scholar
  24. 24.
    Muyldermans S (2001) Rev Mol Biotechnol 74:277–302CrossRefGoogle Scholar
  25. 25.
    Harmsen M, De Haard H (2007) Appl Microbiol Biotechnol 77:13–22CrossRefGoogle Scholar
  26. 26.
    Doyle PJ, Arbabi-Ghahroudi M, Gaudette N, Furzer G, Savard ME, Gleddie S, McLean MD, Mackenzie CR, Hall JC (2008) Mol Immunol 45:3703–3713CrossRefGoogle Scholar
  27. 27.
    van Houwelingen A, De Saeger S, Rusanova T, Waalwijk C, Beekwilder J (2008) World Mycotoxin J 1:407–417CrossRefGoogle Scholar
  28. 28.
    Suzuki T, Munakata Y, Morita K, Shinoda T, Ueda H (2007) Anal Sci 23:65–70CrossRefGoogle Scholar
  29. 29.
    Arduini F, Errico I, Amine A, Micheli L, Palleschi G, Moscone D (2007) Anal Chem 79:3409–3415CrossRefGoogle Scholar
  30. 30.
    Li X, Millson S, Coker R, Evans I (2006) Biotechnol Lett 28:1955–1964CrossRefGoogle Scholar
  31. 31.
    Andreu Y, Castillo JR, de Marcos S, Galbán J (2004) Talanta 64:196–201CrossRefGoogle Scholar
  32. 32.
    Siontorou CG, Nikolelis DP, Miernik A, Krull UJ (1998) Electrochim Acta 43:3611–3617CrossRefGoogle Scholar
  33. 33.
    Andreou VG, Nikolelis DP (1998) Anal Chem 70:2366–2371CrossRefGoogle Scholar
  34. 34.
    Brüggemann O (2002) In: Scheper T (ed) Advances in biochemical engineering and biotechnology. Vol 76. Springer, Berlin, pp 127–163Google Scholar
  35. 35.
    Mahony JO, Nolan K, Smyth MR, Mizaikoff B (2005) Anal Chim Acta 534:31–39CrossRefGoogle Scholar
  36. 36.
    Baggiani C, Anfossi L, Giovannoli C (2007) Anal Chim Acta 591:29–39CrossRefGoogle Scholar
  37. 37.
    Baggiani C, Anfossi L, Giovannoli C (2008) Analyst 133:719–730CrossRefGoogle Scholar
  38. 38.
    Appell M, Maragos CM, Kendra DF (2008) In: Siantar DP, Trucksess MW, Scott PM, Herman EM (eds) Food contaminants: mycotoxins and food allergens. American Chemical Society, Washington, pp 152–169CrossRefGoogle Scholar
  39. 39.
    Weiss R, Freudenschuss M, Krska R, Mizaikoff B (2003) Food Addit Contam 20:386–395CrossRefGoogle Scholar
  40. 40.
    Pascale M, De Girolamo A, Visconti A, Magan N, Chianella I, Piletska EV, Piletsky SA (2008) Anal Chim Acta 609:131–138CrossRefGoogle Scholar
  41. 41.
    Baggiani C, Giraudi G, Vanni A (2002) Bioseparation 10:389–394CrossRefGoogle Scholar
  42. 42.
    Jodlbauer J, Maier NM, Lindner W (2002) J Chromatogr A 945:45–63CrossRefGoogle Scholar
  43. 43.
    Maier NM, Buttinger G, Welhartizki S, Gavioli E, Lindner W (2004) J Chromatogr B 804:103–111CrossRefGoogle Scholar
  44. 44.
    Turner NW, Piletska EV, Karim K, Whitcombe M, Malecha M, Magan N, Baggiani C, Piletsky SA (2004) Biosens Bioelectron 20:1060–1067CrossRefGoogle Scholar
  45. 45.
    Zhou S, Lai E, Miller JD (2004) Anal Bioanal Chem 378:1903–1906CrossRefGoogle Scholar
  46. 46.
    Yu JCC, Lai EPC (2005) React Funct Polym 63:171–176CrossRefGoogle Scholar
  47. 47.
    Wei Y, Qiu L, Owen C, Lai EPC (2007) Sens Instrum Food Qual 1:133–141CrossRefGoogle Scholar
  48. 48.
    Yu JCC, Lai EPC (2007) Food Chem 105:301–310CrossRefGoogle Scholar
  49. 49.
    Appell M, Kendra DF, Kim EK, Maragos CM (2007) Food Addit Contam 24:43–52CrossRefGoogle Scholar
  50. 50.
    Morissette P, Beaulieu M, Vinet B (2000) Clin Chem 46:1516–1518Google Scholar
  51. 51.
    Navarro-Villoslada F, Urraca JL, Moreno-Bondi MC, Orellana G (2007) Sens Actuators B 121:67–73CrossRefGoogle Scholar
  52. 52.
    Urraca JL, Marazuela MD, Merino ER, Orellana G, Moreno-Bondi MC (2006) J Chromatogr A 1116:127–134CrossRefGoogle Scholar
  53. 53.
    Urraca JL, Carbajo MC, Torralvo MJ, González-Vázquez J, Orellana G, Moreno-Bondi MC (2008) Biosens Bioelectron 24:155–161CrossRefGoogle Scholar
  54. 54.
    Urraca J, Marazuela MD, Moreno-Bondi MC (2006) Anal Bioanal Chem 385:1155–1161CrossRefGoogle Scholar
  55. 55.
    Faure K, Delaunay N, Alloncle G, Cotte S, Rocca JL (2007) J Chromatogr A 1149:145–150CrossRefGoogle Scholar
  56. 56.
    Moreno-Bondi MC, Urraca JL, Benito-Peña E, Navarro-Villoslada F, Martins SA, Orellana G, Sellergren B (2007) In: Cutolo A, Culshaw B, López-Higuera JM (eds) Proceedings of SPIE, vol 6619. The International Society for Optical Engineering, Bellingham, pp 66190C1–66190C4Google Scholar
  57. 57.
    Huebner HJ, Phillips TE (2003) J AOAC Intl 86:534–539Google Scholar
  58. 58.
    Puzyr AP, Purtov KV, Shenderova OA, Luo M, Brenner DW, Bondar VS (2007) Doklady Biochem Biophys 417:299–301CrossRefGoogle Scholar
  59. 59.
    Tozzi C, Anfossi L, Baggiani C, Giovannoli C, Giraudi G (2003) Anal Bioanal Chem 375:994–999Google Scholar
  60. 60.
    Giraudi G, Anfossi L, Baggiani C, Giovannoli C, Tozzi C (2007) J Chromatogr A 1175:174–180CrossRefGoogle Scholar
  61. 61.
    Heurich M (2008) PhD dissertation, Cranfield UniversityGoogle Scholar
  62. 62.
    Cruz-Aguado JA, Penner G (2008) Anal Chem 80:8853–8855CrossRefGoogle Scholar
  63. 63.
    Cruz-Aguado JA, Penner G (2008) J Agric Food Chem 56:10456–10461CrossRefGoogle Scholar
  64. 64.
    Francis OJ Jr, Kirschenheuter GP, Ware GM, Carman AS, Kuan SS (1988) J Assoc Off Anal Chem 71:725–728Google Scholar
  65. 65.
    Dall’Asta C, Ingletto G, Corradini R, Galaverna G, Marchelli R (2003) J Inclusion Phenom Macrocyclic Chem 45:257–263CrossRefGoogle Scholar
  66. 66.
    Verrone R, Catucci L, Cosma P, Fini P, Agostiano A, Lippolis V, Pascale M (2007) J Inclusion Phenom Macrocyclic Chem 57:475–479CrossRefGoogle Scholar
  67. 67.
    Dall’Asta C, Faccini A, Galaverna G, Corradini R, Dossena A, Marchelli R (2008) Mycotoxin Res 24:14–18CrossRefGoogle Scholar
  68. 68.
    Goryacheva I, Rusanova TY, Pankin KE (2008) J Anal Chem 63:751–755CrossRefGoogle Scholar
  69. 69.
    Maragos CM, Appell M, Lippolis V, Visconti A, Catucci L, Pascale M (2008) Food Addit Contam 25:164–171CrossRefGoogle Scholar
  70. 70.
    Franco CM, Fente CA, Vázquez BI, Cepeda A, Mahuzier G, Prognon P (1998) J Chromatogr A 815:21–29CrossRefGoogle Scholar
  71. 71.
    Wei J, Okerberg E, Dunlap J, Ly C, Shear JB (2000) Anal Chem 72:1360–1363CrossRefGoogle Scholar
  72. 72.
    Maragos CM, Appell M (2007) J Chromatogr A 1143:252–257CrossRefGoogle Scholar
  73. 73.
    Hishiya T, Shibata M, Kakazu M, Asanuma H, Komiyama M (1999) Macromolecules 32:2265–2269CrossRefGoogle Scholar
  74. 74.
    Galaverna G, Dall’Asta C, Corradini R, Dossena A, Marchelli R (2008) World Mycotoxin J 1:397–406CrossRefGoogle Scholar

Copyright information

© Springer-Verlag 2009

Authors and Affiliations

  1. 1.United States Department of Agriculture, Agricultural Research ServiceNational Center for Agricultural Utilization ResearchPeoriaUSA

Personalised recommendations