Analytical and Bioanalytical Chemistry

, Volume 385, Issue 3, pp 518–524

FloDots: luminescent nanoparticles

  • Gang Yao
  • Lin Wang
  • Yanrong Wu
  • Josh Smith
  • Jinsheng Xu
  • Wenjun Zhao
  • Eunjung Lee
  • Weihong Tan
Review

Abstract

Luminescent dye-doped silica nanoparticles (FloDots) have been developed for ultrasensitive bioanalysis and diagnosis in the past several years. Those novel nanoparticles are highly luminescent and extremely photostable. In this paper, we review the preparation, characterization, bioconjugation and bioapplication of FloDots. All the results clearly demonstrated that FloDots have many advantages over currently used luminescent probes, such as traditional fluorophores and quantum dots.

Keywords

Dye-doped silica nanoparticles Nanotechnology Bioanalysis 

Copyright information

© Springer-Verlag 2006

Authors and Affiliations

  • Gang Yao
    • 1
    • 2
  • Lin Wang
    • 1
  • Yanrong Wu
    • 1
  • Josh Smith
    • 1
  • Jinsheng Xu
    • 3
  • Wenjun Zhao
    • 1
  • Eunjung Lee
    • 1
  • Weihong Tan
    • 1
  1. 1.Center for Research at the Bio/nano Interface, Department of Chemistry and Shands Cancer CenterUniversity of FloridaGainesvilleUSA
  2. 2.Life Science Inc.St. PetersburgUSA
  3. 3.Department of ChemistryHengyang Normal UniversityHengyangPeople’s Republic of China

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