Analytical and Bioanalytical Chemistry

, Volume 382, Issue 7, pp 1698–1701 | Cite as

Preparation of a novel molecularly imprinted polymer using a water-soluble crosslinking agent

  • Takuya KuboEmail author
  • Ken Hosoya
  • Makoto Nomachi
  • Nobuo Tanaka
  • Kunimitsu Kaya
Short Communication


A molecularly imprinted polymer was prepared using a water-soluble crosslinking agent. An ionic complex was utilized as the assembly for the template molecule and the functional monomer, and water as porogenic solvent during preparation of the imprinted polymer. The results of chromatographic evaluations for the prepared polymer suggested that the polymer had much lower hydrophobicity compared with usual octadecyl group bonded silica or the usual molecular imprinted polymer prepared from ethyleneglycol dimethacrylate, and the selective recognition ability for template molecule in the completely aqueous condition.


Molecularly imprinted polymer Water-soluble crosslinking agent Ionic complex Lower hydrophobicity Selective recognition 



This research was financially supported by the Nanotechnology Project of the Ministry of Environment. We thank the NOF Corporation (Japan) for providing the crosslinking agent.


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Copyright information

© Springer-Verlag 2005

Authors and Affiliations

  • Takuya Kubo
    • 1
    Email author
  • Ken Hosoya
    • 2
  • Makoto Nomachi
    • 1
  • Nobuo Tanaka
    • 2
  • Kunimitsu Kaya
    • 1
  1. 1.Graduate School of Environmental StudiesTohoku UniversityAoba-kuJapan
  2. 2.Department of Polymer Science and EngineeringKyoto Institute of TechnologySakyo-ku, Kyoto 606-8585Japan

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