Analytical and Bioanalytical Chemistry

, Volume 382, Issue 4, pp 926–933

Metal-enhanced fluorescence using anisotropic silver nanostructures: critical progress to date

  • Kadir Aslan
  • Joseph R. Lakowicz
  • Chris D. Geddes
Review

DOI: 10.1007/s00216-005-3195-3

Cite this article as:
Aslan, K., Lakowicz, J.R. & Geddes, C.D. Anal Bioanal Chem (2005) 382: 926. doi:10.1007/s00216-005-3195-3

Abstract

In this critical and timely review, the effects of anisotropic silver nanostructures on the emission intensity and photostability of a key fluorophore that is frequently used in many biological assays is examined. The silver nanostructures consist of triangular, rod-like, and fractal-like nanoparticles of silver deposited on conventional glass substrates. The close proximity to silver nanostructures results in greater intensity and photostability of the fluorophore than for fluorophores solely deposited on glass substrates. These new anisotropic silver nanostructure-coated surfaces show much more favorable effects than silver island films or silver colloid-coated substrates. Subsequently, the use of metal-enhanced fluorescence (MEF) for biosensing applications is discussed.

Keywords

Silver nanotriangles Silver nanorods Anisotropic nanoparticles Metal-enhanced fluorescence Radiative decay engineering Increased excitation rate 

Copyright information

© Springer-Verlag 2005

Authors and Affiliations

  • Kadir Aslan
    • 1
  • Joseph R. Lakowicz
    • 2
  • Chris D. Geddes
    • 1
    • 2
  1. 1.Laboratory for Advanced Medical Plasmonics, Medical Biotechnology Center, Institute of FluorescenceUniversity of Maryland Biotechnology InstituteBaltimoreUSA
  2. 2.Department of Biochemistry and Molecular Biology, Center for Fluorescence Spectroscopy, Medical Biotechnology CenterUniversity of Maryland School of MedicineBaltimoreUSA

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