Analytical and Bioanalytical Chemistry

, Volume 378, Issue 8, pp 1922–1928 | Cite as

Electrochemical sensing with electrodes modified with molecularly imprinted polymer films

  • M. C. Blanco-López
  • S. Gutiérrez-Fernández
  • M. J. Lobo-Castañón
  • A. J. Miranda-Ordieres
  • P. Tuñón-BlancoEmail author
Original Paper


This article summarises our work on the development of voltammetric sensors based on molecularly imprinted polymers. Several recognition elements and integration strategies were used:
  1. 1.

    membranes electropolymerised at the electrode surface;

  2. 2.

    casting of polymeric membranes by drop-coating a solution of pre-formed polymer (polyphosphazene) and template in a low-boiling-point solvent on to the electrode surface;

  3. 3.

    preparation of composite membranes containing conductive material (graphite or carbon black), acrylic-type molecularly imprinted polymers (small particle size), and PVC as binder; and

  4. 4.

    in-situ polymerisation of a thin layer of acrylic imprinted polymer deposited on the electrode surface by spin coating.

All the options evaluated offer the possibility of controlling electrode characteristics such as hydrophobic/hydrophilic character, permeability, or film thickness, which are essential for obtaining good sensor performance.


Molecularly imprinted polymers Voltammetric sensors Biomimetics 



Financial support from the Spanish government (Ministerio de Ciencia y Tecnología, project No. BQ-2002–00261) is acknowledged. S. Gutiérrez-Fernández thanks FICYT for a grant.


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Copyright information

© Springer-Verlag 2003

Authors and Affiliations

  • M. C. Blanco-López
    • 1
  • S. Gutiérrez-Fernández
    • 1
  • M. J. Lobo-Castañón
    • 1
  • A. J. Miranda-Ordieres
    • 1
  • P. Tuñón-Blanco
    • 1
    Email author
  1. 1.Departamento de Química Física y Analítica, Facultad de QuímicaUniversidad de OviedoOviedoSpain

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