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Analytical and Bioanalytical Chemistry

, Volume 378, Issue 1, pp 84–88 | Cite as

Target-selective ion-exchange media for highly hydrophilic compounds: a possible solution by use of the “interval immobilization technique”

  • Takuya Kubo
  • Nobuo Tanaka
  • Ken HosoyaEmail author
Paper in Forefront

Abstract

We prepared a crosslinked polymer as a separation and/or adsorption medium for CYN, as shown in Fig. 1. The polymers were evaluated by high-performance liquid chromatography (HPLC) and adsorption was examined under batch conditions. Results from detailed HPLC evaluation and measurement of the difference between the binding affinity for CYN and for other compounds showed the prepared polymer had specific recognition ability for CYN.

Keywords

Ion-exchange media Highly hydrophilic compounds Interval immobilization technique Cylindrospermopsin (CYN) Cyanobacterium hepatotoxin 

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Copyright information

© Springer-Verlag 2003

Authors and Affiliations

  1. 1.Department of Polymer Science and EngineeringKyoto Institute of TechnologySakyo-kuJapan

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