Analytical and Bioanalytical Chemistry

, Volume 375, Issue 8, pp 1116–1123 | Cite as

Novel infrared optical probes for process monitoring and analysis based on next-generation silver halide fibers

  • H. M. HeiseEmail author
  • L. Küpper
  • L. N. Butvina
Special Issue Paper


Mid-infrared spectroscopy has proved to be a powerful method for the study of various samples and chemical media as found in different industrial processes. In general, the analysis of such samples takes advantage of the fact that multiple analytes can be quantified simultaneously and rapidly without the need for additional reagents. When compared to near-infrared spectroscopy, for which quartz fiber probes can be successfully applied, the application of previously used mid-infrared fiber materials was restricted due to deficiencies with regard to their optical transmission and mechanical properties. Progress in the quality of infrared transparent silver halide fibers and their extrusion with different cross-sections enabled us to construct several flexible fiber-optic probes of different geometries which are particularly suitable and inert for process monitoring. Transmission and attenuated total reflection measurement techniques have mainly been employed for the analysis of liquid and gaseous media. One larger field, for which results are reported, is chemical reactor monitoring. Other applications are concerned with bio-reactor monitoring, or quasi-continuous measurements for the food industry. Infrared spectroscopic cosmetic assays for determining the chemical composition of skin-care formulations are a further promising field of application, for which an example is given.


Fourier-transform infrared spectroscopy Silver halide fiber probes Process monitoring Chemical analysis Attenuated total reflection Transmission spectroscopy 



Financial support by the Ministerium für Wissenschaft und Forschung des Landes Nordrhein-Westfalen and the Bundesministerium für Bildung und Forschung is gratefully acknowledged by the first two authors (H.M.H., L.K.). Professor Dr P. McIntyre (School of Applied Sciences, University of Glamorgan, Pontypridd, UK) is thanked for collaboration during the olive oil authentication project, funded in part by the EU contract No. AIR2-CT 92-1224. Finally, Professor Dr D.F. Ihrig (University of Applied Sciences, Iserlohn, Germany) is thanked for the bioreactor samples and Dr W. Pittermann (Henkel KGaA, Düsseldorf, Germany) for the cosmetic creams and vitamin E samples. We are grateful to Drs H. Binder and A. Bader (BASF, Ludwigshafen, Germany) for support in some reaction monitoring experiments.


  1. 1.
    Tate JD, Chauvel P, Guenard RD, Harner R (2002) Process monitoring by mid- and near-infrared Fourier-transform spectroscopy. In: Chalmers JM, Griffiths PR (eds) Handbook of Vibrational Spectroscopy, Vol 4. Wiley, Chichester, pp 2737–2769Google Scholar
  2. 2.
    Vidrine DW (2000) Mid-infrared spectroscopy in chemical process analysis. In: Chalmers JM (ed) Spectroscopy in process analysis. Sheffield Academic Press, Sheffield, 96–138Google Scholar
  3. 3.
    Marazuela MD, Moreno-Bondi MC (2002) Anal Bioanal Chem 372:664–682CrossRefPubMedGoogle Scholar
  4. 4.
    Küpper L, Heise HM, Butvina LN (2001) J Mol Struct 563/564:173–181Google Scholar
  5. 5.
    Littlejohn D, Lucas D, Han L (1999) Appl Spectrosc 53:845–849Google Scholar
  6. 6.
    Hahn P, Tacke M, Jakusch M, Mizaikoff B, Spector O, Katzir A (2001) Appl Spectrosc 55:39–43Google Scholar
  7. 7.
    Bürck J, Roth S, Krämer K, Scholz M, Klaas N (2001) J Hazard Mater 83:11–28CrossRefPubMedGoogle Scholar
  8. 8.
    Creaser CS, Hutchinson WE, Stephenson GR (2002) Sens Actuators B 82:150–157CrossRefGoogle Scholar
  9. 9.
    Butvina L (1998) Polycrystalline fibers. In: Sanghera J, Aggarwal I (eds) Infrared fiber optics. CRC Press, Boca Raton, chap. 6, pp 209–249Google Scholar
  10. 10.
    Butvina LN, Dianov EM, Lichkova NV, Zavgorodnev VN, Küpper L (2000) Proc SPIE 4083:238–253Google Scholar
  11. 11.
    Doak DL, Phillips JA (1999) Biotechnol Progr 15:529–539CrossRefGoogle Scholar
  12. 12.
    Harrington JA (2001) Infrared fiber optics. In: Optics Soc Am (ed) Handbook of optics. McGraw–Hill, New York, chap 14Google Scholar
  13. 13.
    Lu P, Bao X, Whidden T, Lee SY (2000) Appl Optic 39:1112–1117Google Scholar
  14. 14.
    Sadeghi-Jorabchi H, Wood VME, Jeffery F, Bruster-Davies A, Loh N, Coombs D (1994) Spectrosc Eur 6:16–21Google Scholar
  15. 15.
    Uemura T, Nishida K, Sakakida M, Ichinose K, Shimoda S, Shichiri M (1999) Frontiers Med Biol Eng 9:137–153Google Scholar
  16. 16.
    Heise HM, Bittner A, Küpper L, Butvina LN (1997) J Mol Struct 410/411:521–525Google Scholar
  17. 17.
    Heise HM, Küpper L, Butvina LN (1998) Sens Actuators B 51:84–91CrossRefGoogle Scholar
  18. 18.
    Heise HM, Küpper L, Butvina LN (2002) Spectrochim Acta B57:1649–1663Google Scholar
  19. 19.
    Kurte R, Beyer C, Heise HM, Klockow D (2002) Anal Bioanal Chem 373:639–646PubMedGoogle Scholar
  20. 20.
    Artjushenko VG, Lerman AA, Litvinenko EG, Nabatov AO, Konov VI, Kuznetsov RI, Plotnichenko VG, Pylnov IL, Shtein-Margolina VA, Urusovskaja AA, Vojtsekhovsky VV, Zaharov ND, Neuberger W, Moran K (1991) Proc SPIE 1591:83–89Google Scholar
  21. 21.
    Bunimovich D, Shalem S, Katzir A (1997) Appl Optic 36:285–290Google Scholar
  22. 22.
    Wilson RH, Tapp HS (1999) Trends Anal Chem 18:85–93CrossRefGoogle Scholar
  23. 23.
    Küpper L, Heise HM, Lampen P, Davies AN, McIntyre P (2001) Appl Spectrosc 55:563–570Google Scholar
  24. 24.
    Cadet F, Robert C, Offmann B (1997) Appl Spectrosc 51:369–375Google Scholar
  25. 25.
    Heise HM, Küpper L, Pittermann W, Butvina LN (2001) Fresenius J Anal Chem 371:753–757CrossRefPubMedGoogle Scholar

Copyright information

© Springer-Verlag 2003

Authors and Affiliations

  1. 1.Institute of Spectrochemistry and Applied SpectroscopyUniversity of DortmundDortmundGermany
  2. 2.Infrared fiber sensorsAachenGermany
  3. 3.Fiber Optic Research CenterGeneral Physics InstituteMoscowRussia

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