Analytical and Bioanalytical Chemistry

, Volume 372, Issue 1, pp 66–73

Developments in ion mobility spectrometry–mass spectrometry

  • D. Collins
  • M. Lee


Ion mobility spectrometry (IMS) has been used for over 30 years as a sensitive detector of organic compounds. The following is a brief review of IMS and its principles with an emphasis on its usage when coupled to mass spectrometry. Since its inception, IMS has been interfaced with quadrupole, time-of-flight, and Fourier-transform ion cyclotron resonance mass spectrometry. These hybrid instruments have been employed for the analysis of a variety of target analytes, including biomolecules, explosives, chemical warfare degradation products, and illicit drugs.

Ion mobility spectrometry Mass spectrometry Gas-phase electrophoresis Plasma chromatography 


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Copyright information

© Springer-Verlag 2001

Authors and Affiliations

  • D. Collins
    • 1
  • M. Lee
    • 2
  1. 1.Weber State University, Department of Criminal Justice, Ogden, Utah 84408–1206, USAUSA
  2. 2.Brigham Young University, Department of Chemistry and Biochemistry, Provo, Utah 84602–5700, USAUSA

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