, Volume 212, Issue 3, pp 309–320 | Cite as

Attentional bias toward cigarette cues in active smokers

  • Vicki W. Chanon
  • Chandler R. Sours
  • Charlotte A. Boettiger
original investigation



While it is well documented that substance users exhibit attentional bias toward addiction-related stimuli, the exact mechanism remains unclear.


To differentiate between distinct aspects of attentional allocation in the smoking-cue attentional bias observed in smokers.


Active smokers (AS) and non-smoking controls completed spatial cueing tasks with pairs of smoking and neutral pictorial cues to measure attentional capture, and an attentional blink task with either a smoking or neutral image appearing behind the first target (T1) to measure aspects of attention separate from capture. In addition, we tested groups of sports enthusiasts, and non-enthusiasts in corresponding tasks replacing smoking images with sports-related images to address the possibility that effects found in the smoking study were due simply to greater stimulus familiarity.


Smoking cues reflexively capture smokers' attention, as AS showed a greater bias toward smoking cues in short stimulus-onset asynchrony (SOA; the time between the onset of two stimuli) trials, but not in trials with a longer SOA. These effects represent a facilitation of responding to smoking- versus neutral-cued targets, and were absent in the sports control task. The attentional blink effects were similar in the smoking- and sports-cue experiments: the special T1 resulted in better detection of the second target for the smokers and sports enthusiasts.


Stimulus familiarity may contribute to some aspects of attentional bias in regular nicotine users, but selective quick capture of attention by smoking cues may be nicotine-habit specific.


Addiction Attention Attentional blink Attentional capture Inhibition of return Nicotine Spatial cueing Substance abuse Visual 



The authors have no conflict of interest to report. Each participant gave signed informed consent before any sessions were begun, and APA human subjects research guidelines were followed. The experiments were approved by the Institutional Review Board at the University of North Carolina at Chapel Hill, and comply with the current laws of the United States. This work was supported by Award Number KL2RR025746 from the National Center for Research Resources (CAB) and F32DA025442 (VWC). The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Center for Research Resources or the National Institutes of Health.

Supplementary material

213_2010_1953_MOESM1_ESM.doc (26 kb)
ESM 1 (DOC 26 kb)


  1. Attwood AS, O'Sullivan H, Leonards U, Mackintosh B, Munafó MR (2008) Attentional bias training and cue reactivity in cigarette smokers. Addiction 103:1875–1882CrossRefPubMedGoogle Scholar
  2. Bar M, Kassam KS, Ghuman AS, Boshyan J, Schmid AM, Dale AM, Hämäläinen MS, Marinkovic K, Schacter DL, Rosen BR, Halgren E (2006) Top-down facilitation of visual recognition. P Natl Acad Sci 103:449–454CrossRefGoogle Scholar
  3. Bonnel A-M, Prinzmetal W (1998) Dividing attention between the color and the shape of objects. Percept Psychophys 60:113–124PubMedGoogle Scholar
  4. Boyer M, Dickerson M (2003) Attentional bias and addictive behaviour: automaticity in a gambling-specific modified Stroop task. Addiction 98:61–70CrossRefPubMedGoogle Scholar
  5. Bradley BP, Mogg K, Millar NH (2000) Covert and overt orienting of attention to emotional faces in anxiety. Cogn Emotion 14:789–808CrossRefGoogle Scholar
  6. Bradley BP, Mogg K, Wright T, Field M (2003) Attentional bias in drug dependence: vigilance for cigarette-related cues in smokers. Psychol Addict Behav 17:66–72CrossRefPubMedGoogle Scholar
  7. Bradley B, Field M, Mogg K, De Houwer J (2004) Attentional and evaluative biases for smoking cues in nicotine dependence: component processes of biases in visual orienting. Behav Pharmacol 15:29–36CrossRefPubMedGoogle Scholar
  8. Broadbent DE, Broadbent MH (1987) From detection to identification: response to multiple targets in rapid serial visual presentation. Percept Psychophys 42:105–113PubMedGoogle Scholar
  9. Chanon VW, Hopfinger JB (2008) Memory's grip on attention: the influence of item memory on the allocation of attention. Vis Cogn 16:325–340CrossRefGoogle Scholar
  10. Chun MM, Potter MC (1995) A two-stage model for multiple target detection in rapid serial visual presentation. J Exp Psychol Hum Percept Perform 21:109–127CrossRefPubMedGoogle Scholar
  11. Copersino ML, Serper MR, Vadhan N, Goldberg BR, Richarme D, Chou JC, Stitzer M, Cancro R (2004) Cocaine craving and attentional bias in cocaine-dependent schizophrenic patients. Psychiatry Res 128:209–218CrossRefPubMedGoogle Scholar
  12. Corbetta M, Tansy AP, Stanley CM, Astafiev SV, Snyder AZ, Shulman GL (2005) A functionalMRI study of preparatory signals for spatial location and objects. Neuropsychologia 43:2041–2056CrossRefPubMedGoogle Scholar
  13. Coward RS, Poliakoff E, O'Boyle DJ, Lowe C (2004) The contribution of non-ocular response inhibition to visual inhibition of return. Exp Brain Res 155:124–128CrossRefPubMedGoogle Scholar
  14. Cox WM, Hogan LM, Kristian MR, Race JH (2002) Alcohol attentional bias as a predictor of alcohol abusers' treatment outcome. Drug Alcohol Depend 68:237–243CrossRefPubMedGoogle Scholar
  15. Cox WM, Pothos EM, Hosier SG (2007) Cognitive-motivational predictors of excessive drinkers' success in changing. Psychopharmacology (Berl) 192:499–510CrossRefGoogle Scholar
  16. Delorme A, Richard G, Fabre-Thorpe M (2000) Ultra-rapid categorisation of natural scenes does not rely on colour cues: a study in monkeys and humans. Vis Res 40:2187–2200CrossRefPubMedGoogle Scholar
  17. Duka T, Townshend JM (2004) The priming effect of alcohol pre-load on attentional bias to alcohol-related stimuli. Psychopharmacology (Berl) 176:353–361CrossRefGoogle Scholar
  18. Ehrman RN, Robbins SJ, Bromwell MA, Lankford ME, Monterosso JR, O'Brien CP (2002) Comparing attentional bias to smoking cues in current smokers, former smokers, and non-smokers using a dot-probe task. Drug Alcohol Depend 67:185–191CrossRefPubMedGoogle Scholar
  19. Fabre-Thorpe M, Richard G, Thorpe SJ (1998) Rapid categorization of natural images by rhesus monkeys. NeuroReport 9:303–308CrossRefPubMedGoogle Scholar
  20. Fan J, McCandliss BD, Sommer T, Raz A, Posner MI (2002) Testing the efficiency and independence of attentional networks. J Cogn Neurosci 14:340–347CrossRefPubMedGoogle Scholar
  21. Field M, Eastwood B (2005) Experimental manipulation of attentional bias increases the motivation to drink alcohol. Psychopharmacology (Berl) 183:350–357CrossRefGoogle Scholar
  22. Field M, Mogg K, Bradley BP (2005a) Craving and cognitive biases for alcohol cues in social drinkers. Alcohol Alcohol 40:504–510PubMedGoogle Scholar
  23. Field M, Mogg K, Bradley BP (2005b) Alcohol increases cognitive biases for smoking cues in smokers. Psychopharmacology (Berl) 180:63–72CrossRefGoogle Scholar
  24. Field M, Mogg K, Zetteler J, Bradley BP (2004) Attentional biases for alcohol cues in heavy and light social drinkers: the roles of initial orienting and maintained attention. Psychopharmacology (Berl) 176:88–93CrossRefGoogle Scholar
  25. Field M, Eastwood B, Bradley BP, Mogg K (2006) Selective processing of cannabis cues in regular cannabis users. Drug Alcohol Depend 85:75–82CrossRefPubMedGoogle Scholar
  26. Field M, Munafó MR, Franken IH (2009) A meta-analytic investigation of the relationship between attentional bias and subjective craving in substance abuse. Psychol Bull 135:589–607CrossRefPubMedGoogle Scholar
  27. Foulds J, Stapleton J, Swettenham J, Bell N, McSorley K, Russell MA (1996) Cognitive performance effects of subcutaneous nicotine in smokers and never-smokers. Psychopharmacology (Berl) 127:31–38CrossRefGoogle Scholar
  28. Franken IHA (2003) Drug craving and addiction: integrating psychological and neuropsychopharmacological approaches. Prog Neuro-Psychopharmacol Biol Psychiatry 27:563–579CrossRefGoogle Scholar
  29. Franken IH, Kroon LY, Wiers RW, Jansen A (2000) Selective cognitive processing of drug cues in heroin dependence. J Psychopharmacol 14:395–400CrossRefPubMedGoogle Scholar
  30. Hester R, Dixon V, Garavan H (2006) A consistent attentional bias for drug-related material in active cocaine users across word and picture versions of the emotional Stroop task. Drug Alcohol Depend 81:251–257CrossRefPubMedGoogle Scholar
  31. Hopfinger JB, Mangun GR (1998) Reflexive attention modulates processing of visual stimuli in human extrastriate cortex. Psychol Sci 9:441–447CrossRefGoogle Scholar
  32. Hopfinger JB, Maxwell JS (2005) Appearing and disappearing stimuli trigger a reflexive modulation of visual cortical activity. Brain Res Cogn Brain Res 25:48–56CrossRefPubMedGoogle Scholar
  33. Hopfinger JB, West VM (2006) Interactions between endogenous and exogenous attention on cortical visual processing. Neuroimage 31:774–789CrossRefPubMedGoogle Scholar
  34. Istvan J, Matarazzo JD (1984) Tobacco, alcohol, and caffeine use—a review of their interrelationships. Psychol Bull 95:301–326CrossRefPubMedGoogle Scholar
  35. Jones BC, Jones BT, Blundell L, Bruce G (2002) Social users of alcohol and cannabis who detect substance-related changes in a change blindness paradigm report higher levels of use than those detecting substance-neutral changes. Psychopharmacology (Berl) 165:93–96CrossRefGoogle Scholar
  36. Jones BT, Jones BC, Smith H, Copley N (2003) A flicker paradigm for inducing change blindness reveals alcohol and cannabis information processing biases in social users. Addiction 98:235–244CrossRefPubMedGoogle Scholar
  37. Jones BT, Bruce G, Livingstone S, Reed E (2006) Alcohol-related attentional bias in problem drinkers with the flicker change blindness paradigm. Psychol Addict Behav 20:171–177CrossRefPubMedGoogle Scholar
  38. Jonides J, Yantis S (1988) Uniqueness of abrupt visual onset in capturing attention. Percept Psychophys 43:346–354PubMedGoogle Scholar
  39. Klein RM (2000) Inhibition of return. Trends Cogn Sci 4:138–147CrossRefPubMedGoogle Scholar
  40. Koelega HS (1993) Stimulant drugs and vigilance performance: a review. Psychopharmacology (Berl) 111:1–16CrossRefGoogle Scholar
  41. Koster EH, Crombez G, Verschuere B, De Houwer J (2004) Selective attention to threat in the dot probe paradigm: differentiating vigilance and difficulty to disengage. Behav Res Ther 42:1183–1192CrossRefPubMedGoogle Scholar
  42. Liu N, Li B, Sun N, Ma Y (2008) Effects of addiction-associated and affective stimuli on the attentional blink in a sample of abstinent opiate dependent patients. J Psychopharmacol 22:64–70PubMedGoogle Scholar
  43. Lorist MM, Snel J, Kok A, Mulder G (1994) Influence of caffeine on selective attention in well-rested and fatigued subjects. Psychophysiology 31:525–534CrossRefPubMedGoogle Scholar
  44. Lubman DI, Peters LA, Mogg K, Bradley BP, Deakin JF (2000) Attentional bias for drug cues in opiate dependence. Psychol Med 30:169–175CrossRefPubMedGoogle Scholar
  45. Mancuso G, Warburton DM, Melen M, Sherwood N, Tirelli E (1999) Selective effects of nicotine on attentional processes. Psychopharmacology (Berl) 146:199–204CrossRefGoogle Scholar
  46. Marissen MA, Franken IH, Waters AJ, Blanken P, van den Brink W, Hendriks VM (2006) Attentional bias predicts heroin relapse following treatment. Addiction 101:1306–1312CrossRefPubMedGoogle Scholar
  47. McCusker CG, Gettings B (1997) Automaticity of cognitive biases in addictive behaviours: further evidence with gamblers. Br J Clin Psychol 36(Pt 4):543–554PubMedGoogle Scholar
  48. Mogg K, Bradley BP (2002) Selective processing of smoking-related cues in smokers: manipulation of deprivation level and comparison of three measures of processing bias. J Psychopharmacol 16:385–392CrossRefPubMedGoogle Scholar
  49. Mogg K, Bradley BP, Field M, De Houwer J (2003) Eye movements to smoking-related pictures in smokers: relationship between attentional biases and implicit and explicit measures of stimulus valence. Addiction 98:825–836CrossRefPubMedGoogle Scholar
  50. Mogg K, Field M, Bradley BP (2005) Attentional and approach biases for smoking cues in smokers: an investigation of competing theoretical views of addiction. Psychopharmacology (Berl) 180:333–341CrossRefGoogle Scholar
  51. Most SB, Junge JA (2008) Don't look back: retroactive, dynamic costs and benefits of emotional capture. Vis Cogn 16:262–278CrossRefGoogle Scholar
  52. Most SB, Chun MM, Widders DM, Zald DH (2005) Attentional rubbernecking: cognitive control and personality in emotion-induced blindness. In, pp 654–661: Psychonomic Soc IncGoogle Scholar
  53. Most SB, Smith SD, Cooter AB, Levy BN, Zald DH (2007) The naked truth: positive, arousing distractors impair rapid target perception. Cogn Emotion 21:964–981CrossRefGoogle Scholar
  54. Muller MM, Andersen SK, Keil A (2008) Time course of competition for visual processing resources between emotional pictures and foreground task. Cereb Cortex 18:1892–1899CrossRefPubMedGoogle Scholar
  55. Munafo MR, Johnstone EC, Mackintosh B (2005) Association of serotonin transporter genotype with selective processing of smoking-related stimuli in current smokers and ex-smokers. Nicotine Tob Res 7:773–778CrossRefPubMedGoogle Scholar
  56. Newhouse PA, Potter A, Singh A (2004) Effects of nicotinic stimulation on cognitive performance. Curr Opin Pharmacol 4:36–46CrossRefPubMedGoogle Scholar
  57. Noel X, Colmant M, Van Der Linden M, Bechara A, Bullens Q, Hanak C, Verbanck P (2006) Time course of attention for alcohol cues in abstinent alcoholic patients: the role of initial orienting. Alcohol Clin Exp Res 30:1871–1877CrossRefPubMedGoogle Scholar
  58. O'Craven KM, Downing PE, Kanwisher N (1999) fRMI evidence for objects as the units of attentional selection. Nature 401:584–587CrossRefPubMedGoogle Scholar
  59. Parks EL, Hopfinger JB (2008) Hold it! Memory affects attentional dwell time. Psychon Bull Rev 15:1128–1134CrossRefPubMedGoogle Scholar
  60. Pekkanen J, Kuulasmaa K, Evans A, Zhang M for the WHO MONICA Project (1992) Quality assessment of smoking data in the first surveys of the WHO MONICA Project. MONICA Memo 209A, JanuaryGoogle Scholar
  61. Posner M, Cohen Y (1984) Components of visual orienting. In: Bouma H, Bouwhis D (eds) Attent perform vol. X. Erlbaum, Hillsdale, pp 531–556Google Scholar
  62. Posner MI, Walker JA, Friedrich FJ, Rafal RD (1984) Effects of parietal injury on covert orienting of attention. J Neurosci 4:1863–1874PubMedGoogle Scholar
  63. Pratt J, McAuliffe J (2001) The effects of onsets and offsets on visual attention. Psychological Research 65:185–191CrossRefPubMedGoogle Scholar
  64. Raymond JE, Shapiro KL, Arnell KM (1992) Temporary suppression of visual processing in an RSVP task: an attentional blink? J Exp Psychol Hum Percept Perform 18:849–860CrossRefPubMedGoogle Scholar
  65. Reeves A, Fuller H, Fine EM (2005) The role of attention in binding shape to color. Vis Res 45:3343–3355CrossRefPubMedGoogle Scholar
  66. Robinson TE, Berridge KC (1993) The neural basis of drug craving: an incentive-sensitization theory of addiction. Brain Res Brain Res Rev 18:247–291CrossRefPubMedGoogle Scholar
  67. Sakurai Y, Kanazawa I (2002) Acute effects of cigarettes in non-deprived smokers on memory, calculation and executive functions. Hum Psychopharmacol 17:369–373CrossRefPubMedGoogle Scholar
  68. Sharma D, Albery IP, Cook C (2001) Selective attentional bias to alcohol related stimuli in problem drinkers and non-problem drinkers. Addiction 96:285–295CrossRefPubMedGoogle Scholar
  69. Stetter F, Ackermann K, Bizer A, Straube ER, Mann K (1995) Effects of disease-related cues in alcoholic inpatients: results of a controlled “Alcohol Stroop” study. Alcohol Clin Exp Res 19:593–599CrossRefPubMedGoogle Scholar
  70. Stolerman IP, Mirza NR, Shoaib M (1995) Nicotine psychopharmacology: addiction, cognition and neuroadaptation. Med Res Rev 15:47–72CrossRefPubMedGoogle Scholar
  71. Streeter CC, Terhune DB, Whitfield TH, Gruber S, Sarid-Segal O, Silveri MM, Tzilos G, Afshar M, Rouse ED, Tian H, Renshaw PF, Ciraulo DA, Yurgelun-Todd DA (2008) Performance on the Stroop predicts treatment compliance in cocaine-dependent individuals. Neuropsychopharmacology 33:827–836CrossRefPubMedGoogle Scholar
  72. Theeuwes J (1991) Exogenous and endogenous control of attention—the effect of visual onsets and offsets. Percept Psychophys 49:83–90PubMedGoogle Scholar
  73. Tibboel H, De Houwer J, Field M (2009) Reduced attentional blink for alcohol-related stimuli in heavy social drinkers. J PsychopharmacolGoogle Scholar
  74. Townshend JM, Duka T (2001) Attentional bias associated with alcohol cues: differences between heavy and occasional social drinkers. Psychopharmacology (Berl) 157:67–74CrossRefGoogle Scholar
  75. Waters AJ, Feyerabend C (2000) Determinants and effects of attentional bias in smokers. Psychol Addict Behav 14:111–120CrossRefPubMedGoogle Scholar
  76. Wesnes K, Warburton DM (1984) The effects of cigarettes of varying yield on rapid information processing performance. Psychopharmacology (Berl) 82:338–342CrossRefGoogle Scholar
  77. Yeomans MR, Javaherian S, Tovey HM, Stafford LD (2005) Attentional bias for caffeine-related stimuli in high but not moderate or non-caffeine consumers. Psychopharmacology (Berl) 181:477–485CrossRefGoogle Scholar
  78. Zhou B (2008) Disentangling perceptual and motor components in inhibition of return. Cogn Process 9:175–187CrossRefPubMedGoogle Scholar

Copyright information

© Springer-Verlag 2010

Authors and Affiliations

  • Vicki W. Chanon
    • 1
  • Chandler R. Sours
    • 1
  • Charlotte A. Boettiger
    • 1
    • 2
    • 3
  1. 1.Department of PsychologyUniversity of North Carolina at Chapel HillChapel HillUSA
  2. 2.Biomedical Research Imaging Center, Bowels Center for Alcohol StudiesUniversity of North Carolina at Chapel HillChapel HillUSA
  3. 3.Neurobiology CurriculumUniversity of North Carolina at Chapel HillChapel HillUSA

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