Individual differences in acute alcohol impairment of inhibitory control predict ad libitum alcohol consumption
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Research has begun to examine how acute cognitive impairment from alcohol could contribute to alcohol abuse. Specifically, alcohol-induced impairment of inhibitory control could compromise the drinker’s ability to stop the self-administration of alcohol, increasing the risk of binge drinking.
The present study was designed to test this hypothesis by examining the relation between acute alcohol impairment of inhibitory control and alcohol consumption during a single drinking episode.
Materials and methods
Twenty-six healthy adults performed a cued go/no-go task that measured inhibitory control. The study tested the degree to which their inhibitory control was impaired by a moderate dose of alcohol (0.65 g/kg) versus a placebo and the extent to which individual differences in this impairment predicted levels of alcohol consumption as assessed by ad lib drinking in the laboratory.
In accord with the hypothesis, greater impairment of inhibitory control from alcohol was associated with increased ad lib consumption.
Acute impairment of inhibitory control might be an important cognitive effect that contributes to abuse in addition to the positive rewarding effects of the drug.
KeywordsAlcohol Inhibition Ad lib consumption Cued go/no-go task Neurocognitive mechanisms Abuse potential
- Fillmore MT (2007) Acute alcohol induced impairment of cognitive functions: past and present findings. International Journal of Disability and Human Development 6:115–125Google Scholar
- Gray JA (1976) The behavioral inhibition system: a possible substrate for anxiety. In: Feldman MP, Broadhurst A (eds) Theoretical and experimental bases of the behavior therapies. Wiley, London, pp 3–41Google Scholar
- Logan GD (1994) On the ability to inhibit thought and action: a user’s guide to the stop-signal paradigm. In: Dagenback D, Carr TH (eds) Inhibitory processes in attention, memory, and language. Academic, San Diego, pp 189–239Google Scholar
- McKim WA (2007) Drugs and behavior: an introduction to behavioral pharmacology, 6th edn. Prentice Hall, New JerseyGoogle Scholar
- National Institute on Alcohol Abuse and Alcoholism (2004) NIAAA council approves definition of binge drinking. NIAAA Newsletter, No. 3, Winter 2004Google Scholar
- Schneider W, Eschman A, Zuccolotto A (2002) E-prime user’s guide. Psychology Software Tools, Pittsburgh, PAGoogle Scholar
- Seltzer ML, Vinokur A, van Rooijen L (1975) A self-administered Short Michigan Alcoholism Screening Test (SMAST). J Stud Alcohol 36:117–126Google Scholar
- Vogel-Sprott M (1992) Alcohol tolerance and social drinking: learning the consequences. Guilford, New YorkGoogle Scholar
- Wiers RW, Stacy AW (2006) Implicit cognition and addiction: an introduction. In: Wiers RW, Stacy AW (eds) Handbook of implicit cognition and addiction. Sage, London, pp 1–8Google Scholar