The role of attentional bias in mediating human drug-seeking behaviour
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The attentional bias for drug cues is believed to be a causal cognitive process mediating human drug seeking and relapse.
Objectives, methods and results
To test this claim, we trained smokers on a tobacco conditioning procedure in which the conditioned stimulus (or S+) acquired parallel control of an attentional bias (measured with an eye tracker), tobacco expectancy and instrumental tobacco-seeking behaviour. Although this correlation between measures may be regarded as consistent with the claim that the attentional bias for the S+ mediated tobacco seeking, when a secondary task was added in the test phase, the attentional bias for the S+ was abolished, yet the control of tobacco expectancy and tobacco seeking remained intact.
This dissociation suggests that the attentional bias for drug cues is not necessary for the control that drug cues exert over drug-seeking behaviour. The question raised by these data is what function does the attentional bias serve if it does not mediate drug seeking?
KeywordsHuman attentional bias Drug conditioning Drug seeking Interference Addiction Abuse Attention Conditioned Behavior
This work was supported by a Biotechnology and Biological Research Council grant (BBS/B/09384) and was completed in the lab of Theodora Duka at the University of Sussex. The authors would like to thank Dr. Mathew Field and Dr. Marcus Munafo for their helpful comments on an earlier draft of this manuscript.
- Field M (2006) Attentional biases in drug abuse and addiction: cognitive mechanisms, causes, consequences, and implications. In: Munafo MR, Albery IP (eds) Cognition and Addiction. Oxford University Press, OxfordGoogle Scholar
- Hitsman B, Mackillop J, Lingford-Hughes A, Williams T, Ahmad F, Adams S, Nutt DJ, Munafo MR (2007) Effects of acute tyrosine/phenylalanine depletion on the selective processing of smoking-related cues and the relative value of cigarettes in smokers. Psychopharmacology 196:611–621PubMedCrossRefGoogle Scholar
- Hogarth L, Dickinson A, Austin A, Brown C, Duka T (2008) Attention and expectation in human predictive learning: the role of uncertainty. Quarterly Journal of Experimental Psychology B (in press)Google Scholar
- Kessler K Controlling the EyeLink eye tracker with E-Prime. Retrieved July 2007, from http://www.eyelinkinfo.com/contact.php.
- Pothos EM, Calitri R, Tapper K, Brunstrom JM, Rogers PJ (2008) Comparing measures of cognitive bias relating to eating behavior. Applied Cognitive Psychology (in press)Google Scholar
- Premack D, Collier G (1966) Duration of looking and number of brief looks as dependent variables. Psychon Sci 4:81–82Google Scholar