, Volume 187, Issue 3, pp 284–286 | Cite as

Commentary on: Psilocybin can occasion mystical-type experiences having substantial and sustained personal meaning and spiritual significance by Griffiths et al.

  • David E. NicholsEmail author

The article by Griffiths et al. in this issue of Psychopharmacology should make all scientists interested in human psychopharmacology sit up and take notice. It is the first well-designed, placebo-controlled, clinical study in more than four decades to examine the psychological consequences of the effects of the hallucinogenic (psychedelic) agent known as psilocybin. In fact, one would be hard-pressed to find a single study of psychedelics from any earlier era that was as well-done or as meaningful. Perhaps more importantly, despite the notion by many people that psychedelics are nothing more than troublesome drugs of abuse, the present study convincingly demonstrates that, when used appropriately, these compounds can produce remarkable, possibly beneficial, effects that certainly deserve further study.

Although many people seem to believe that “psychedelics” simply appeared during the turbulent 1960s, in fact the use of these materials spans back through many millennia of human...


Psilocybin Terminal Cancer Patient Psychedelic Drug Theological Seminary Transcendental State 
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Copyright information

© Springer-Verlag 2006

Authors and Affiliations

  1. 1.Department of Medicinal Chemistry and Molecular PharmacologyPurdue University School of Pharmacy and Pharmaceutical SciencesWest LafayetteUSA

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