, Volume 171, Issue 1, pp 75–80 | Cite as

Early intervention in schizophrenia: three frameworks for guiding ethical inquiry



Psychiatric research is making important strides toward early detection and treatment of schizophrenia. Discovery of genetic markers, identifiable prodromes, and low-risk interventions fuel this vital scientific movement. At the same time, investigators and clinicians are studying the ethical questions that arise whenever the bounds of diagnosis and treatment are evolving rapidly. This ethical analysis generally falls within three dominant frameworks of bioethics: the conceptualization of disease, scientific uncertainty, and risk-factor ethics. These frameworks are explored as potential guides for directing ethical inquiry in early intervention.


Bioethics Intervention Genetic markers Risk factors 



The author's work in research ethics is supported by an NIH Career Development Award (NIH K01MH01850). The opinions expressed do not necessarily reflect those of the NIH.


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Copyright information

© Springer-Verlag 2003

Authors and Affiliations

  1. 1.Department of PsychiatryUniversity of Massachusetts Medical SchoolWorcesterUSA

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