Archives of Microbiology

, Volume 173, Issue 1, pp 76–77

Salmonella typhimurium forms adenylcobamide and 2-methyladenylcobamide, but no detectable cobalamin during strictly anaerobic growth

  • B. Keck
  • P. Renz
Short communication

DOI: 10.1007/s002030050011

Cite this article as:
Keck, B. & Renz, P. Arch Microbiol (2000) 173: 76. doi:10.1007/s002030050011


Under microaerophilic conditions Salmonella typhimurium LT2 synthesizes cobalamin, during which 5,6-dimethylbenzimidazole is formed from riboflavin. We report here that in an anoxic environment S. typhimurium did not form cobalamin, but rather adenylcobamide, 2-methyladenylcobamide, and cobyric acid. This indicated that S. typhimurium, like other microorganisms that synthesize 5,6-dimethylbenzimidazole from riboflavin, requires oxygen for the formation of the cobalamin base.

Key words 5,6-Dimethylbenzimidazole Factor A Pseudovitamin B12 Riboflavin Salmonella ¶typhimurium Vitamin B12 

Copyright information

© Springer-Verlag Berlin Heidelberg 2000

Authors and Affiliations

  • B. Keck
    • 1
  • P. Renz
    • 1
  1. 1.Institut für Biologische Chemie und Ernährungswissenschaft, Universität Hohenheim, Garbenstrasse 30, D-70599 Stuttgart, Germany e-mail:, Tel.: +49-711-4592284, Fax: +49-711-4592283DE

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