Identification of a lipoarabinomannan-like lipoglycan in the actinomycete Gordonia bronchialis
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- Garton, N.J. & Sutcliffe, I.C. Arch Microbiol (2006) 184: 425. doi:10.1007/s00203-005-0050-z
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The cell envelopes of actinomycetes contain lipidated macroamphiphiles, of which the most extensively characterised are the lipoarabinomannans of mycobacteria and related bacteria. We have investigated the mycolic acid-containing actinomycete Gordonia bronchialis and identified the presence of a lipoarabinomannan-like lipoglycan. The extraction and purification procedures recovered a second amphiphilic fraction with properties suggesting a phosphatidylinositol mannoside, consistent with studies of other Gordonia species.