IOF Regional 7th Asia-Pacific Osteoporosis Conference Sydney, Australia 2018 – Plenary Lecture Abstracts
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CAN FRAX BE IMPROVED?
J. A. Kanis1,2
1Centre for Metabolic Bone Diseases, University of Sheffield Medical School, Sheffield, United Kingdom, 2Mary McKillop Health Institute, Australian Catholic University, Melbourne, Australia
FRAX® is a computer-based algorithm (http://www.shef.ac.uk/FRAX) that calculates the 10-year probability of a major fracture (hip, clinical spine, humerus or wrist fracture) and the 10-year probability of hip. Fracture risk is calculated from age, body mass index and well validated dichotomized risk factors. Femoral neck bone mineral density can be optionally input to enhance fracture risk prediction. The first 8 models were launched in 2008 and there are currently 68 models in 63 countries covering more than 80% of the world population. With the increasing geographic representation of FRAX, uptake has risen progressively and there are upwards of 3 million calculations undertaken each year.
A probability calculation is of no use unless guidance is provided on...