Osteoporosis International

, Volume 23, Issue 7, pp 1859–1865 | Cite as

Mortality after vertebral fracture in Korea

Analysis of the National Claim Registry
  • Y.-K. Lee
  • S. Jang
  • S. Jang
  • H. J. Lee
  • C. Park
  • Y.-C. Ha
  • D.-Y. KimEmail author
Original Article



The present study evaluates the incidence and mortality of vertebral fractures in Korea, using data from the Health Insurance Review Assessment Service, which includes nationwide information entrusted by Korean government.


A vertebral compression fracture is a serious complication associated with osteoporosis of the spine. We evaluated the incidence of vertebral fracture and subsequent mortality in South Korea, using nationwide data from the Health Insurance Review and Assessment Service (HIRA).


All new visits or admissions to clinics or hospitals for fractures were recorded in nationwide cohort by the Korean HIRA using International Classification of Disease, tenth Revision (ICD-10) code. The incidence of vertebral fracture and excess mortality associated with vertebral fracture were evaluated, in men and women aged 50 years or more between 2005 and 2008. Standardized mortality ratio (SMR) was calculated to determine excess mortality associated with vertebral fracture.


The crude overall incidence of vertebral fractures was 984 per 100,000 person years from 2005 to 2008. The overall mortality rate at 3 months, 6 months, 1 year, and 2 years after vertebral fracture in men (5.56%, 9.41%, 14.6%, and 20.61%, respectively) were higher than that in women (2.41%, 4.36%, 7.16%, and 10.48%, respectively). In both genders, the age-specific mortality rates were more than those of the general population. The SMR was highest during the first 3 months and gradually declined to 2.53 in men and 1.86 in women at the 2-year period.


The incidence of vertebral fracture in South Korea was comparable with other countries such as Switzerland, and the mortality after vertebral fracture is higher than that of normal populations. The incidence of osteoporotic vertebral fracture and following high mortality are likely to become serious socioeconomic problems.


Incidence Mortality Osteoporosis Vertebral fracture 



This study was supported by the Korean Health Insurance Review and Assessment Service (HIRA) and conducted using data from the Korean National Health Insurance Claims Database.

Conflicts of interest

This study was supported by the Korean Health Insurance Review and Assessment Service (HIRA) and conducted using data from the Korean National Health Insurance Claims Database.


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Copyright information

© International Osteoporosis Foundation and National Osteoporosis Foundation 2011

Authors and Affiliations

  • Y.-K. Lee
    • 1
  • S. Jang
    • 5
  • S. Jang
    • 6
  • H. J. Lee
    • 2
  • C. Park
    • 2
  • Y.-C. Ha
    • 3
  • D.-Y. Kim
    • 4
    Email author
  1. 1.Department of Orthopaedic SurgerySeoul National University Bundang HospitalSeoulSouth Korea
  2. 2.Health Insurance Review and Assessment ServiceSeoulSouth Korea
  3. 3.Department of Orthopaedic SurgeryChung-Ang University College of MedicineSeoulSouth Korea
  4. 4.Department of Nuclear MedicineKyung Hee University HospitalSeoulSouth Korea
  5. 5.Inje University College of PharmacyGyeongsangnam-doSouth Korea
  6. 6.Graduate School of Public HealthSeoul National UniversitySeoulSouth Korea

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