Osteoporosis International

, Volume 21, Issue 7, pp 1151–1154 | Cite as

IOF position statement: vitamin D recommendations for older adults

  • B. Dawson-HughesEmail author
  • A. Mithal
  • J.-P. Bonjour
  • S. Boonen
  • P. Burckhardt
  • G. E.-H. Fuleihan
  • R. G. Josse
  • P. Lips
  • J. Morales-Torres
  • N. Yoshimura
Position Paper


This position paper of the International Osteoporosis Foundation makes recommendations for vitamin D nutrition in elderly men and women from an evidence-based perspective.


Musculoskeletal health Requirement Vitamin D 


Conflicts of interest



  1. 1.
    Durazo-Arvizu RA, Dawson-Hughes B, Sempos CT, Yetley EA, Looker AC, Cao G, Harris SS, Burt VL, Carriquiry AL, Picciano MF (2010) Three-phase model harmonizes estimates of the maximal suppression of parathyroid hormone by 25-hydroxyvitamin D in persons 65 years of age and older. J Nutr. doi: 10.3945/jm.109.116681 PubMedGoogle Scholar
  2. 2.
    Heaney RP, Davies KM, Chen TC, Holick MF, Barger-Lux MJ (2003) Human serum 25-hydroxycholecalciferol response to extended oral dosing with cholecalciferol. Am J Clin Nutr 77:204–210PubMedGoogle Scholar
  3. 3.
    Wortsman J, Matsuoka LY, Chen TC, Lu Z, Holick MF (2000) Decreased bioavailability of vitamin D in obesity. Am J Clin Nutr 72:690–693 [erratum appears in Am J Clin Nutr. 2003 May;77(5):1342]PubMedGoogle Scholar
  4. 4.
    Blum M, Dallal GE, Dawson-Hughes B (2008) Body size and serum 25 hydroxy vitamin D response to oral supplements in healthy older adults. J Am Coll Nutr 27:274–279PubMedGoogle Scholar
  5. 5.
    Harris SS, Dawson-Hughes B (1998) The association of oral contraceptive use with plasma 25-hydroxyvitamin D levels. J Am Coll Nutr 17:282–284PubMedGoogle Scholar
  6. 6.
    Harris SS, Dawson-Hughes B (2002) Plasma vitamin D and 25OHD responses of young and old men to supplementation with vitamin D3. J Am Coll Nutr 21:357–362PubMedGoogle Scholar
  7. 7.
    Goussous R, Song L, Dallal G, Dawson-Hughes B (2005) The effect of calcium intake on the vitamin D requirement. J Clin Endocrinol Metab 90:707–711CrossRefPubMedGoogle Scholar
  8. 8.
    Boonen S, Lips P, Bouillon R, Bischoff-Ferrari HA, Vanderschueren D, Haentjens P (2007) Need for additional calcium to reduce the risk of hip fracture with vitamin D supplementation: evidence from a comparative metaanalysis of randomized controlled trials. J Clin Endocrinol Metab 92:1415–1423CrossRefPubMedGoogle Scholar
  9. 9.
    May W, Parris R, Beck C, Fassett J, Greenberg R, Guenther F, Kramer G, Wise S, Gills T, Colbert J, Gettings R, MacDonald B (2000) Definitions of terms and modes used at NIST for value-assignment of reference materials for chemical measurements. In Technology NIoSa (ed). US Government Printing Office, GaithersburgGoogle Scholar
  10. 10.
    Flicker L, MacInnis RJ, Stein MS, Scherer SC, Mead KE, Nowson CA, Thomas J, Lowndes C, Hopper JL, Wark JD (2005) Should older people in residential care receive vitamin D to prevent falls? Results of a randomized trial. J Am Geriatr Soc 53:1881–1888CrossRefPubMedGoogle Scholar
  11. 11.
    Visser M, Deeg DJ, Lips P (2003) Low vitamin D and high parathyroid hormone levels as determinants of loss of muscle strength and muscle mass (sarcopenia): the Longitudinal Aging Study Amsterdam. J Clin Endocrinol Metab 88:5766–5772CrossRefPubMedGoogle Scholar
  12. 12.
    Bischoff-Ferrari HA, Dawson-Hughes B, Staehelin HB, Orav EJ, Stuck AE, Theiler R, Wong JB, Egli A, Kiel DP, Henschkowski J (2009) Fall prevention with supplemental and active forms of vitamin D: a meta-analysis of randomised controlled trials. Br Med J 339:b3692CrossRefGoogle Scholar
  13. 13.
    Ooms ME, Roos JC, Bezemer PD, van der Vijgh WJ, Bouter LM, Lips P (1995) Prevention of bone loss by vitamin D supplementation in elderly women: a randomized double-blind trial. J Clin Endocrinolol Metab 80:1052–1058CrossRefGoogle Scholar
  14. 14.
    Bischoff-Ferrari HA, Willett WC, Wong JB, Giovannucci E, Dietrich T, Dawson-Hughes B (2005) Fracture prevention by vitamin D supplementation: a meta-analysis of randomized controlled trials. J Am Med Assoc 293:2257–2264CrossRefGoogle Scholar
  15. 15.
    Mithal A, Wahl DA, Bonjour JP, Burckhardt P, Dawson-Hughes B, Eisman JA, El-Hajj Fuleihan G, Josse RG, Lips P, Morales-Torres J (2009) Global vitamin D status and determinants of hypovitaminosis D. Osteoporos Int 20:1807–1820CrossRefPubMedGoogle Scholar
  16. 16.
    El-Hajj Fuleihan G (2009) Vitamin D deficiency in the Middle East and its health consequences. Clin Rev Bone Miner Metab 7:77–93CrossRefGoogle Scholar
  17. 17.
    Holick MF, Biancuzzo RM, Chen TC, Klein EK, Young A, Bibuld D, Reitz R, Salameh W, Ameri A, Tannenbaum AD (2008) Vitamin D2 is as effective as vitamin D3 in maintaining circulating concentrations of 25-hydroxyvitamin D. J Clin Endocrinol Metab 93:677–681CrossRefPubMedGoogle Scholar
  18. 18.
    Trang HM, Cole DE, Rubin LA, Pierratos A, Siu S, Vieth R (1998) Evidence that vitamin D3 increases serum 25-hydroxyvitamin D more efficiently than does vitamin D2. Am J Clin Nutr 68:854–858PubMedGoogle Scholar

Copyright information

© International Osteoporosis Foundation and National Osteoporosis Foundation 2010

Authors and Affiliations

  • B. Dawson-Hughes
    • 1
    Email author
  • A. Mithal
    • 2
  • J.-P. Bonjour
    • 3
  • S. Boonen
    • 4
  • P. Burckhardt
    • 5
  • G. E.-H. Fuleihan
    • 6
  • R. G. Josse
    • 7
  • P. Lips
    • 8
  • J. Morales-Torres
    • 9
  • N. Yoshimura
    • 10
  1. 1.Jean Mayer USDA Human Nutrition Research Center on AgingTufts UniversityBostonUSA
  2. 2.Indraprastha Apollo HospitalsSarita ViharNew DelhiIndia
  3. 3.University Hospital, Division of Bone DiseasesUniversity Hospitals and Faculty of MedicineGenevaSwitzerland
  4. 4.Centre for Metabolic Bone Diseases and Division of Geriatric MedicineUniversity of LeuvenLeuvenBelgium
  5. 5.Association Suisse contre l’OstéoporoseClinique Bois-CerfLausanneSwitzerland
  6. 6.Calcium Metabolism and Osteoporosis ProgramAmerican University of Beirut-Medical CenterBeirutLebanon
  7. 7.Division of Endocrinology and MetabolismUniversity of Toronto, St Michael’s Hospital Health CentreTorontoCanada
  8. 8.Division of Internal MedicineEndocrine Section, VU University Medical CenterAmsterdamNetherlands
  9. 9.Hospital Aranda de la ParraLeónMexico
  10. 10.Department of Joint Disease Research, 22nd Century Medical and Research CenterUniversity of TokyoTokyoJapan

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