Osteoporosis International

, Volume 22, Issue 2, pp 499–505 | Cite as

Physical activity in middle-aged women and hip fracture risk: the UFO study

  • U. Englund
  • P. Nordström
  • J. Nilsson
  • G. Bucht
  • U. Björnstig
  • G. Hallmans
  • O. Svensson
  • U. Pettersson
Original Article



In a population-based case-control study, we demonstrate that middle-aged women who were active with walking or in different physical spare time activities were at lower risk of later sustaining a hip fracture compared to more sedentary women.


In middle-aged women participating in the Umeå Fracture and Osteoporosis (UFO) study, we investigated whether physical activity is associated with a subsequent decreased risk of sustaining a hip fracture.


The UFO study is a nested case-control study investigating associations between bone markers, lifestyle, and osteoporotic fractures. We identified 81 female hip fracture cases that had reported lifestyle data before they sustained their fracture. Each case was compared with two female controls who were identified from the same cohort and matched for age and week of reporting data, yielding a total cohort of 237 subjects. Mean age at baseline was 57.2 ± 5.0 years, and mean age at fracture was 65.4 ± 6.4 years.


Conditional logistic regression analysis with adjustments for height, weight, smoking, and menopausal status showed that subjects who were regularly active with walking or had a moderate or high frequency of physical spare time activities (i.e. berry/mushroom picking and snow shovelling) were at reduced risk of sustaining a hip fracture (OR 0.14; 95% CI; 0.05–0.53 for walking and OR 0.19; 95% CI; 0.08–0.46, OR 0.17, 95% CI; 0.05–0.64 for moderate and high frequency of spare time activities, respectively) compared to more sedentary women.


An active lifestyle in middle age seems to reduce the risk of future hip fracture. Possible mechanisms may include improved muscle strength, coordination, and balance resulting in a decreased risk of falling and perhaps also direct skeletal benefits.


Epidemiology Hip fracture Physical activity Risk factors Women 


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Copyright information

© International Osteoporosis Foundation and National Osteoporosis Foundation 2010

Authors and Affiliations

  • U. Englund
    • 1
  • P. Nordström
    • 1
  • J. Nilsson
    • 2
  • G. Bucht
    • 1
  • U. Björnstig
    • 3
  • G. Hallmans
    • 2
  • O. Svensson
    • 3
  • U. Pettersson
    • 4
  1. 1.Department of Community Medicine and RehabilitationUmeå UniversityUmeåSweden
  2. 2.Department of Public Health and Clinical MedicineUmeå UniversityUmeåSweden
  3. 3.Department of Surgical and Perioperative ScienceUmeå UniversityUmeåSweden
  4. 4.Department of Pharmacology and Clinical NeuroscienceUmeå UniversityUmeåSweden

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