Osteoporosis International

, Volume 14, Issue 10, pp 828–834 | Cite as

The effect of milk supplementation on bone mineral density in postmenopausal Chinese women in Malaysia

  • W. S. S. CheeEmail author
  • A. R. Suriah
  • S. P. Chan
  • Y. Zaitun
  • Y. M. Chan
Original Article


Dietary studies often report low calcium intake amongst post-menopausal Malaysian women and calcium deficiency has been implicated as part of the etiology of age-related bone loss leading to osteoporosis. Therefore, the objective of this study was to examine the effectiveness of high calcium skimmed milk (Anlene Gold™, New Zealand Milk, Wellington, New Zealand) to reduce bone loss in Chinese postmenopausal women. Two hundred subjects aged 55–65 years and who were more than 5 years postmenopausal were randomized to a milk group and control group. The milk group consumed 50 g of high calcium skimmed milk powder daily, which contained 1200 mg calcium (taken as two glasses of milk a day). The control group continued with their usual diet. Using repeated measures ANCOVA, the milk supplement was found to significantly reduce the percentage of bone loss at the total body compared to the control group at 24 months (control −1.04%, milk −0.13%; P<0.001). At the lumbar spine, the percentage of bone loss in the control group was significantly higher (−0.90%) when compared to the milk (−0.13%) supplemented group at 24 months (P<0.05). Similarly, milk supplementation reduced the percentage of bone loss at the femoral neck (control −1.21%, milk 0.51%) (P<0.01) and total hip (control −2.17%, milk −0.50%) (P<0.01). The supplemented group did not experience any significant weight gain over the 24 months. The serum 25-hydroxy vitamin D level improved significantly (P<0.01) from 69.1±16.1 nmol/l at baseline to 86.4±22.0 nmol/l at 24 months in the milk group. In conclusion, ingestion of high calcium skimmed milk was effective in reducing the rate of bone loss at clinically important lumbar spine and hip sites in postmenopausal Chinese women in Malaysia. Supplementing with milk had additional benefits of improving the serum 25-hydroxy vitamin D status of the subjects.


Bone mineral density Calcium Milk supplementation Parathyroid hormone Postmenopausal Malaysian women Serum 25-hydroxy vitamin D 



We are grateful to Professor Najib and Mr. Karuthan Chinna for assisting with the statistical analyses and Professor Ian Reid for his comments on the manuscript. The study was funded by New Zealand Milk.


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Copyright information

© International Osteoporosis Foundation and National Osteoporosis Foundation 2003

Authors and Affiliations

  • W. S. S. Chee
    • 1
    Email author
  • A. R. Suriah
    • 2
  • S. P. Chan
    • 3
  • Y. Zaitun
    • 4
  • Y. M. Chan
    • 4
  1. 1.Department of Nutrition & Dietetics, Faculty of Allied Health SciencesNational University of MalaysiaKuala LumpurMalaysia
  2. 2.Program of Food Science, School of Chemical Science and Food Technology, Faculty of Science and TechnologyNational University of MalaysiaBangiMalaysia
  3. 3.Department of Medicine, Faculty of MedicineUniversity of MalaysiaKuala LumpurMalaysia
  4. 4.Department of Nutrition and Health Science, Faculty of Medicine and Health SciencesPutra University MalaysiaSerdangMalaysia

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