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International Urogynecology Journal

, Volume 29, Issue 4, pp 489–495 | Cite as

Incidence of and factors associated with anticholinergic drug use among Norwegian women with urinary incontinence

  • Siri A. Mauseth
  • Svetlana Skurtveit
  • Arnulf Langhammer
  • Olav Spigset
Original Article
  • 211 Downloads

Abstract

Introduction and hypothesis

The aims of this study were to investigate patterns of prescribing anticholinergic drugs among women with urinary incontinence (UI) and to identify factors associated with prescription of these drugs.

Methods

We analysed questionnaire data on UI from 21,735 women older than 20 years who participated in a cross-sectional population-based study in Nord-Trøndelag county, Norway (the HUNT study). These data were linked at the individual level to a national prescription database, and analysed using a multivariate logistic regression model.

Results

Among the women with UI, 4.5% had been prescribed an anticholinergic drug during the previous 12 months. Prescription was most frequent in women with urge UI (10.5%) and mixed UI (7.0%). Of women with UI without treatment with an anticholinergic drug, 1.8% obtained such a prescription during the subsequent 12 months, corresponding to 3.1% of women with urge UI and 3.0% of women with mixed UI. Characteristics significantly associated with starting treatment were age above 50 years, urge or mixed UI, severe or very severe symptoms, consumption of four or more cups of coffee per day, and having visited a doctor for UI. No association was found with marital status, parity, smoking, alcohol, body mass index or anxiety/depression.

Conclusions

In this population-based study, 4.5% of women with UI were prescribed an anticholinergic drug, and the 12-month incidence of starting treatment was 1.8%. Age above 50 years, urge or mixed UI, severe symptoms, high coffee consumption and having visited a doctor for UI were factors associated with first-time drug prescription.

Keywords

Anticholinergic drugs Drug treatment Epidemiology Health survey Prescription patterns Urinary incontinence 

Notes

Funding

This study was supported by a research grant from the Norwegian University of Science and Technology.

Compliance with ethical standards

Conflicts of interest

None.

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Copyright information

© The International Urogynecological Association 2017

Authors and Affiliations

  1. 1.Department of Clinical and Molecular Medicine, Faculty of Medicine and Health SciencesNorwegian University of Science and TechnologyTrondheimNorway
  2. 2.Department of PharmacoepidemiologyNorwegian Institute of Public HealthOsloNorway
  3. 3.Department of Public Health and Nursing and General Practice, Faculty of MedicineNorwegian University of Science and TechnologyTrondheimNorway
  4. 4.Department of Clinical PharmacologySt. Olav University HospitalTrondheimNorway

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