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International Urogynecology Journal

, Volume 23, Issue 4, pp 459–466 | Cite as

Quantifying vaginal tissue elasticity under normal and prolapse conditions by tactile imaging

  • Vladimir Egorov
  • Heather van Raalte
  • Vincent Lucente
Original Article

Abstract

Introduction and hypothesis

Vaginal tactile imaging (VTI) is based on principles similar to those of manual palpation. The objective of this study is to assess the clinical suitability of new approach for imaging and tissue elasticity quantification under normal and prolapse conditions.

Methods

The study subjects included 31 women with normal and prolapse conditions. The tissue elasticity (Young’s modulus) was calculated from spatial gradients in the resulting 3-D tactile images.

Results

Average values for tissue elasticity for the anterior and posterior compartments for normal conditions were 7.4 ± 4.3 kPa and 6.2 ± 3.1 kPa respectively. For Stage III prolapse the average values for tissue elasticity for anterior and posterior compartments were 1.8 ± 0.7 kPa and 1.8 ± 0.5 kPa respectively.

Conclusions

VTI may serve as a means for 3-D imaging of the vagina and a quantitative assessment of vaginal tissue elasticity, providing important information for furthering our understanding of pelvic organ prolapse and surgical treatment.

Keywords

Biomechanical properties Elasticity Prolapse Vaginal tissue Tactile imaging 

Abbreviations

ANOVA

One-way analysis of variance

E

Young’s modulus

POP

Pelvic organ prolapse

POP-Q

Pelvic organ prolapse quantification system

MRI

Magnetic resonance imaging

VTI

Vaginal tactile imager

Notes

Acknowledgements

The authors would like to thank Noune Sarvazyan, PhD, and Armen Sarvazyan, PhD, DSc, for editing assistant and support of this research; Randee Weed, MS, RDMS, for clinical research documentation and data management; Robin Haff, RN, BSN, for study coordination; and Milind Patel for technical assistance with the device. The work was supported by the National Institute on Aging, USA, grant AG034714.

Conflicts of interest

None.

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Copyright information

© The International Urogynecological Association 2011

Authors and Affiliations

  • Vladimir Egorov
    • 1
  • Heather van Raalte
    • 2
  • Vincent Lucente
    • 3
  1. 1.Artann LaboratoriesTrentonUSA
  2. 2.Princeton UrogynecologyPrincetonUSA
  3. 3.The Institute for Female Pelvic Medicine & Reconstructive SurgeryAllentownUSA

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