Prevalence of “low-count” bacteriuria in female urinary incontinence versus continent female controls: a cross-sectional study

  • Colin A. Walsh
  • Anne Siddins
  • Katrina Parkin
  • Chinmoy Mukerjee
  • Kate H. Moore
Original Article

Abstract

Introduction and hypothesis

Older studies suggesting an association between detrusor overactivity and bacteriuria used an outdated microbiological threshold. We hypothesised that bacteriuria ≥103 CFU/ml would be more prevalent in women with urinary incontinence than continent controls.

Methods

A prospective, cross-sectional study of prevalence of bacteriuria ≥103 colony-forming units (CFU)/ml on catheter specimens. Sample estimates suggested 62 women per arm would yield 80% power. Multivariate regression analysis was performed using risk factors including, age, diabetes, menopausal status, sexual activity and cystocele.

Results

Among 213 participants, bacteriuria ≥103 CFU/ml was more prevalent in incontinent women than continent controls (odds ratio [OR] 4.06; p = 0.036). Two thirds of bacteriuric specimens grew “low-count” bacteriuria. On multivariate analysis, only cystocele ≥ grade II was independently associated with bacteriuria (p = 0.025). On sub-analysis by diagnosis, the only significant finding was with bladder oversensitivity (OR 13.8; p = 0.0017).

Conclusions

Bacteriuria, including “low-count” bacteriuria, is more prevalent in urinary incontinence when compared to continent female controls.

Keywords

Bacteriuria Incontinence Low count Risk factor Urinary tract infection 

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Copyright information

© The International Urogynecological Association 2011

Authors and Affiliations

  • Colin A. Walsh
    • 1
  • Anne Siddins
    • 1
  • Katrina Parkin
    • 1
  • Chinmoy Mukerjee
    • 2
  • Kate H. Moore
    • 1
  1. 1.Department of UrogynaecologySt George Hospital, University of New South WalesSydneyAustralia
  2. 2.Department of MicrobiologySt George HospitalSydneyAustralia

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