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International Urogynecology Journal

, Volume 21, Issue 5, pp 523–528 | Cite as

Validation of the Patient Global Impression of Improvement (PGI-I) for urogenital prolapse

  • Sushma Srikrishna
  • Dudley Robinson
  • Linda Cardozo
Original Article

Abstract

Introduction and hypothesis

Currently, there is no global outcome assessment index in prolapse research. Patient Global Impression of Improvement (PGI-I) has only been validated in incontinence. Our aim was to validate its use following prolapse surgery.

Methods

Women with prolapse were recruited from waiting lists and assessed objectively (pelvic organ prolapse quantification system (POP-Q)). Quality of life (QoL) was assessed with prolapse QoL questionnaire (pQoL). Patient goal achievement (visual analogue scale (VAS)) determined subjective satisfaction and PGI-I indicated overall satisfaction. We established construct validity of PGI-I by correlating final PGI-I response with other measures of response, measured at 1 year: (POP-Q/pQoL/VAS)

Results

There was excellent test—retest reliability and correlation between PGI-I and other outcome measures.

Conclusion

We believe this is the first study validating PGI-I as a global index of response to prolapse surgery. This may be a valuable addition not only in clinical practice but also in trials comparing surgical interventions.

Keywords

Construct validity Global index Outcome assessment Prolapse PGI-I Reliability 

Notes

Conflicts of interest

Sushma Srikrishna

Speaker Honorarium: Recordati

Consultant: Astellas

Travel grant to attend ICS: Boston Scientific, Recordati

Dudley Robinson

Consultant: Astellas, Ferring, Gynaecare, Uroplasty, Pfizer, Recordati, Novo-Nordisk

Speaker Honorarium: Astellas, Ferring, Gynaecare, Uroplasty, Pfizer, Recordati

Trial participation: Astellas, Pfizer

Linda Cardozo

Consultant: Astellas, Pfizer, Rottapharm, Schering-Plough

Speaker Honorarium: Astellas, Pfizer, Rottapharm, SCA

Trial Participation: Astellas, Pfizer, Bioexcell

Research grant: Pfizer

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Copyright information

© The International Urogynecological Association 2009

Authors and Affiliations

  • Sushma Srikrishna
    • 1
  • Dudley Robinson
    • 1
  • Linda Cardozo
    • 1
  1. 1.Department of UrogynaecologyKing’s College HospitalLondonUK

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