International Urogynecology Journal

, Volume 21, Issue 4, pp 467–473

Long-term results of vaginal repairs with and without xenograft reinforcement

Original Article


Introduction and hypothesis

The aim of this paper is to study if xenograft reinforcement of vaginal repair reduces recurrence of prolapse.


Results 1–5 years after vaginal repair were studied in 41 cases with xenograft and in 82 matched controls without. Symptoms were evaluated by a validated questionnaire and anatomy by pelvic organ prolapse quantification (POPQ).


Significant more cases, 97% versus 81% controls, felt cured or much improved (p = 0.02); 11% of cases and 19% of controls had POP symptoms, POPQ > −1 was found in 31% cases and 24% controls. Defining recurrence as POPQ > −1 plus symptoms revealed recurrence in 3% of cases and 12% controls. None of the recurrence rates was significantly different for cases versus controls. No vaginal erosions were seen. Previous surgery was a significant risk factor with odds ratio 7.3 for another recurrence.


Recurrence rates defined by POPQ plus symptoms were low compared to literature. Xenograft reinforcement might improve results.


Vaginal repair Xenograft Surgisis Pelvic organ prolapse Recurrent prolapse Definition of prolapse 

Copyright information

© The International Urogynecological Association 2009

Authors and Affiliations

  • Lone Mouritsen
    • 1
  • Manuela Kronschnabl
    • 1
  • Gunnar Lose
    • 1
  1. 1.Department of Gynecology and Obstetrics, Herlev HospitalUniversity of CopenhagenCopenhagenDenmark

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