Urodynamic testing and interstitial cystitis/painful bladder syndrome
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Introduction and hypothesis
The objective of this study is to evaluate the relationship between symptom severity in interstitial cystitis/painful bladder syndrome, urodynamic testing (UDT), and cystoscopy.
Charts of subjects who underwent cystoscopy and bladder overdistention (BOD) from January 2006 to July 2007 were reviewed for data points, questionnaires, UDT, and BOD findings. The independent T test and Mann–Whitney U test were performed between questionnaires, urodynamic data, and cystoscopic findings.
Significantly lower volumes on all UDT parameters and higher scores on the interstitial cystitis problem index and pain Likert scale were found in subjects who felt pain with filling on UDT. Significantly lower median volumes for certain urodynamic parameters were found in subjects with high pain Likert scores and O'leary–Sant indices and those with grade 3 glomerulations and anesthetic bladder capacities of less than 600 mL on BOD.
UDT may be a useful adjunctive test in the evaluation of patients with irritative voiding symptoms.
KeywordsInterstitial cystitis Painful bladder syndrome Urodynamics
Interstitial cystitis/painful bladder syndrome
Maximum cystometric capacity
Interstitial cystitis problem index
Interstitial cystitis symptom index
Conflicts of interest
Dr. Whitmore: Consultant for Pfizer, Inc, consultant for Astellas Pharmaceutical US, Inc, Research for Boston Scientific