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International Urogynecology Journal

, Volume 20, Issue 5, pp 489–497 | Cite as

Predictors of outcomes in the treatment of urge urinary incontinence in women

  • Holly E. RichterEmail author
  • Kathryn L. Burgio
  • Toby C. Chai
  • Stephen R. Kraus
  • Yan Xu
  • Lee Nyberg
  • Linda Brubaker
Original Article

Abstract

Introduction and hypothesis

Women with urge predominant urinary incontinence received active intervention (drug therapy alone or combined with behavioral therapy) for 10 weeks, then stopped all therapy and were followed for 6 months more. In this planned secondary analysis, we aimed to identify predictors of therapeutic success at 10 weeks (≥70% reduction in incontinence) and of ability to discontinue treatment and sustain improvements 6 months later.

Methods

Using data from 307 women, we performed logistic regression to identify predictors for outcomes described above.

Results

After controlling for group, only younger age was associated with short-term success (OR 0.8, 95% CI 0.66, 0.96). At 6 months, controlling for group and short-term outcome, only greater anterior vaginal wall prolapse was associated with successful discontinuation (POP-Q point Aa; OR 1.33, 95% CI 1.03, 1.7).

Conclusion

These findings are not of sufficient strength to justify withholding conservative therapies but might be used to promote realistic expectations when counseling patients.

Keywords

Urge urinary incontinence Randomized trial Predictors of outcome 

Notes

Conflicts of interest

None

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Copyright information

© The International Urogynecological Association 2009

Authors and Affiliations

  • Holly E. Richter
    • 1
    • 8
    Email author
  • Kathryn L. Burgio
    • 2
  • Toby C. Chai
    • 3
  • Stephen R. Kraus
    • 4
  • Yan Xu
    • 5
  • Lee Nyberg
    • 6
  • Linda Brubaker
    • 7
  1. 1.University of Alabama at BirminghamBirminghamUSA
  2. 2.Department of Veteran’s Affairs Medical CenterBirmingham/Atlanta Geriatric Research, Education and Clinical CenterBirminghamUSA
  3. 3.University of MarylandBaltimoreUSA
  4. 4.University of Texas Health Science Center at San AntonioSan AntonioUSA
  5. 5.New England Research InstituteWatertownUSA
  6. 6.National Institute Diabetes and Digestive and Kidney DiseasesBethesdaUSA
  7. 7.Loyola UniversityChicagoUSA
  8. 8.Division Women’s Pelvic Medicine and Reconstructive Surgery, Department Of Obstetrics and GynecologyUniversity of Alabama at BirminghamBirminghamUSA

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